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For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.
Table des matières
The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of Lipids.- Oxysterols and Oxysterol-Binding Proteins in Cellular Lipid Metabolism.- Cellular Lipid Traffic and Lipid Transporters: Regulation of Efflux and HDL Formation.- Bile Acids and Their Role in Cholesterol Homeostasis.- Cholesterol Trafficking in the Brain.- Intracellular Cholesterol Transport.- Role of the Endothelium in Lipoprotein Metabolism.- Receptor-Mediated Endocytosis and Intracellular Trafficking of Lipoproteins.- Angiopoietin-Like Proteins and Lipid Metabolism.- Thyroid Hormones and Lipid Metabolism: Thyromimetics as Anti-Atherosclerotic Agents?.- Adipokines: Regulators of Lipid Metabolism.- Cellular Cholesterol Transport-Microdomains, Molecular Acceptors and Mechanisms.- The Ins and Outs of Adipose Tissue.
Résumé
For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.
