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Zusatztext "The first integrated reference for functional protein microarrays! this book helps you not only meet the challenges but also excel in your field." - In Anticancer Research! September/ October 2007! Vol. 27! No. 5A Informationen zum Autor Paul F. Predki Klappentext An ideal text for biotechnologists! protein chemists! and biochemists! Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays! including basic principles! methods! and applications. The book discusses the generation of functional protein content and describes both standard and state-of-the-art fabrication methods. It reviews current and next generation approaches to assay detection and presents a wide range of applications! from biomolecular interaction discovery and characterization to immune response profiling. The book also addresses several fundamental computational issues! bioinformatics anddata analysis. Zusammenfassung Explores various aspects of functional protein microarrays, including basic principles, methods, and applications. This book discusses the generation of functional protein content and describes fabrication methods. It presents a range of applications, from biomolecular interaction discovery and characterization to immune response profiling. Inhaltsverzeichnis Functional Protein Content for Microarrays High-Throughput Gene Cloning Using the Gateway® Technology! S.N. Peterson! P. Burr! G. Tsegaye! and P. Venepally Protein Expression for MicroArrays! H.H. Yim! T.G. Chappell! and S.H. Harwood Emerging Trend: Cell-Free Protein Expression! F. Katzen and W. Kudlicki Fabrication of Functional Protein Microarrays The Critical Role of Surface Chemistry in Protein Microarrays! A. Guo and X.-Y. Zhu Fabrication of Sol-Gel-Derived Protein Microarrays for Diagnostics and Screening! N. Rupcich and J.D. Brennan Printing and QC of Functional Protein Microarrays! D. Shen! F.X. Zhou! and B. Schweitzer Protein Engineering for Surface Attachment! A. Girish! G.Y.J. Chen! and S.Q. Yao Protein In Situ Arrays through Cell-Free Protein Synthesis! M. He! F. Khan! E. Palmer! M. Wang! and M.J. Taussig Detection Methods for Protein Microarrays Fluorescent Detection Methods for Protein Microarrays! S. Roman and S. Clarke Functional Analysis of Protein Interactions Using Surface Plasmon Resonance-Based Microarrays! A. McWhirter and S. Löfås Leaving the Surface Behind: At the Intersection of Protein Microarrays and Mass Spectrometry! D.P. Chandler! D.S. Schabacker! S. Bavykin! and I.M. Gavin High-Resolution Label-Free Detection Applied to Protein Microarray Research! L.G. Laing and B. Cunningham Applications of Functional Protein Microarrays Studying Protein-Protein Interactions with Protein Microarrays: Rapid Identification of 14-3-3 Protein Binding Partners! J.-i. Satoh A Combined Force of Chemical Genetics and Protein Microarrays! H. Zhu and J. Huang Antibody Profiling for Protein Drug Development and Clinical Development! S.H. Herrmann Humoral Response Profiling Using Protein Microarrays! A. Sreekumar! B.S. Taylor! X. Wang! D. Lubman! and A.M. Chinnaiyan DNA Interactions with Arrayed Proteins! M. Snapyan and V. Sakanyan G Protein-Coupled Receptor Microarrays for Drug Discovery! J. Salon! M. Johnson! B. Rasnow! G. Biddlecome! Y. Hong! B. Webb! Y. Fang! and J. Lahiri Kinase Substrate Identification Using Yeast Protein Microarrays! G. Devgan and M. Snyder Bioinformatics & Data Analysis Protein Microarray Image Analysis! M. Ruan The Analysis of Protein Arrays! B. Love Evaluating Precision and Recall in Functional Protein Arrays! K. Robison Visualization of Protein Microarray Data! K. Clancy Index ...
