Fetal and Neonatal Physiology, 2-Volume Set

Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this 2-volume resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice.
The 5^th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner.

• Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants.
• Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology.
• Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more.

• Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
• Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors.
• 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis.
• New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place.
• In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.

Table des matières

Section I - Genetics and Embryology

1. Basic Genetic Principles


2. Prenatal Diagnosis


3. Basic Embryology


4. Regulation of Embryogenesis


5. The Extracellular Matrix in Development


6. Stem Cell Biology


7. Apoptotic Cell Death


8. Angiogenesis


9. Epigenetics
Section II - Placenta and Intrauterine Environment


10. Placental Development


11. Regulation of the Placental Circulation


12. Mechanisms of Transfer Across the Human Placenta


13. Endocrine and Paracrine Function of the Human Placenta


14. Fetal and Maternal Responses to Intrauterine Infection


15. Fetal Origins of Adult Disease: A Classic Hypothesis with New Relevance


16. Physiologic Effects of Multiple Pregnancy on Mother and Fetus


17. Placental function in intrauterine growth restriction
Section III - Developmental Pharmacology and Pharmacokinetics


18. Basic Pharmacologic Principles


19. Principles of Pharmacokinetics


20. Physicochemical and Structural Properties Regulating Placental Drug Transfer


21. Pharmacogenetics


22. Drug Distribution in Fetal Life


23. Drug Transfer During Breastfeeding
Section IV - Intrauterine and Postnatal Growth


24. Circulatory and Metabolic Changes Accompanying Fetal Growth Restriction


25. Endocrine Factors Affecting Neonatal Growth


26. Human Milk Composition and Function in the Infant


27. Physiology of Lactation
Section V - Perinatal Iron, Mineral, and Vitamin Metabolism


28. Fetal and Neonatal Iron Metabolism


29. Neonatal Calcium, Phosphorus, and Magnesium Homeostasis


30. Zinc in the Fetus and Neonate


31. Vitamin A Metabolism in the Fetus and Neonate


32. Vitamin E Metabolism in the Fetus and Newborn Infant


33. Vitamin K Metabolism in the Fetus and Neonate
Section VI - Lipid Metabolism


34. Maternal-Fetal Transfer of Lipid Metabolites


35. Brown Adipose Tissue: Development and Function


36. Lipids as an Energy Source for the Premature and Full-Term Neonate


37. Ketone Body Production and Metabolism in the Fetus and Neonate


38. Long-Chain Fatty Acids in the Developing Retina and Brain
Section VII - Carbohydrate Metabolism


39. Metabolism of Glucose and Methods of Investigation in the Fetus and Newborn


40. Carbohydrate Metabolism During Pregnancy


41. Oxygen Consumption and General Carbohydrate Metabolism of the Fetus


42. Role of Glucoregulatory Hormones in Hepatic Glucose Metabolism During the Perinatal Period


43. Cell Glucose Transport and Glucose Handling During Fetal and Neonatal Development
Section VIII - Protein Metabolism


44. General Concepts of Protein Metabolism


45. Fetal Requirements and Placental Transfer of Nitrogenous Compounds
Section IX - Thermoregulation


46. Temperature Control in Newborn Infants


47. Responses of the Fetus and Neonate to Hypothermia
Section X - Skin


48. Structure and Development of Skin and Cutaneous Appendages


49. Physiologic Development of the Skin
Section XI - Fetal and Neonatal Cardiovascular Physiology


50. Cardiovascular Development


51. Developmental Electrophysiology in the Fetus and Neonate


52. Developmental Biology of the Pulmonary Vasculature


53. Development of the Gastrointestinal Circulation in the Fetus and Newborn


54. Physiology of Congenital Heart Disease in the Neonate


55. Neural Regulation of Blood Pressure During Fetal and Newborn Life


56. Developmental Effects on Fetal Circulation


57. Mechanisms Regulating

Commentaire

"There are no comparable books in this field and this one should hold a unique place as a reference for both physician scientists and clinicians. The new section on the pathophysiology of neonatal disease adds value to this already incomparable text."
-Jay P. Goldsmith, MD (Tulane University School of Medicine), Doody's Score: 96 - 4 Stars!

Détails du produit

• Auteurs: Steven H. Abman, William Benitz, Richard Polin, David H. Rowitch
• Edition: Elsevier, München
• Langues: Anglais
• Format d'édition: Livre Relié
• Sortie: 01.01.2016
• EAN: 9780323352147
• ISBN: 978-0-323-35214-7