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Nanocrystals have been established as an important cancer diagnosis and therapeutic tool due to their ability to deliver poorly soluble drugs with sustained release, low toxicity, and flexibility of administration. In this book, the importance and current status of nanocrystals in cancer therapy are presented, along with challenges, and future prospects.
The book focuses on several therapies of nanocrystals, including anticancer, immunotherapy, radiotherapy, biotheranostics, targeted therapy, photothermal, and photodynamic. Further, different imaging and diagnostics using nanocrystals are mentioned, including magnetic resonance imaging (MRI), computed tomography (CT), biosensing, and luminescence. Finally, the limitations and potential solutions of nanocrystals in the field of cancer theranostics are also discussed.
Table des matières
Chapter 1: Introduction.- Chapter 2: Types of Nanocrystals, synthesis and properties: Organic nanocrystals, Inorganic nanocrystals, Hybrid Nanocrystals.- Chapter 3: Nanocrystals application in cancer therapy: Nanocrystals as drug delivery vehicles; Nanocrystals in targeted therapy; Nanocrystals as anticancer agents.- Chapter 4: Immunomodulation, immunotherapy and biotherapeutics through nanocrystals.- Chapter 5: Rediotherapeutics applications of nanocrystals: PTT, PDT.- Chapter 6: Imaging (magnetic resonance imaging (MRI), computed tomography (CT), biosensing, and luminescence), diagnostics and theranostics applications of nanocrystals.- Chapter 7: Biophysical characterization of Nanocrystals.- Chapter 8: Toxicity, Clinical Studies of Nanocrystals, Conclusion and Future Scope.
A propos de l'auteur
Sudip Mukherjee, Ph.D., MRSC, is an Assistant Professor at the Indian Institute of Technology, BHU. Dr. Mukherjee serves as an Associate Editor for BMC Cancer and Frontiers in Chemistry. Dr. Mukherjee is a member of Royal Society of Chemistry, UK (MRSC). He has published 4 books and over 50 articles. He has 10 US patents filed/granted and has been part of cell engineering-based technologies that is licensed for clinical trials. His research interests include the development of advanced biomaterials for cell therapy and drug/gene delivery in diabetes, cancer theranostics, angiogenesis, and immunomodulatory applications.
Boram Kim is currently pursuing her Ph.D. in Bioengineering at the Rice University. She completed her B.S. in Chemical Engineering at Dongguk University and received her master's degree in Biomedical Science at Soonchunhyang University, where she researched developing biomaterials for tissue engineering and bone regeneration. She has published over 24 research articles. Her thesis work focuses on developing immunomodulatory biomaterials for islet transplantation. She is interested in designing advanced biomaterials and medical devices to improve outcomes in clinical translation for cell-based therapeutics to treat chronic autoimmune diseases.
Andrea Hernandez is a graduate student at The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences (GSBS) where she is pursuing a doctoral degree in Immunology. She is a recipient of a NIDCR Diversity Supplement, which encourages students from underrepresented backgrounds to work towards a scientific career. In her thesis, Andrea is focusing on using a novel peptide nanofiber hydrogel-based platform for intratumoral delivery of immunomodulatory therapeutics to treat Head and Neck Squamous Cell Cancers. She has contributed to more than 5 articles and poster presentations.
Résumé
Nanocrystals have been established as an important cancer diagnosis and therapeutic tool due to their ability to deliver poorly soluble drugs with sustained release, low toxicity, and flexibility of administration. In this book, the importance and current status of nanocrystals in cancer therapy are presented, along with challenges, and future prospects.
The book focuses on several therapies of nanocrystals, including anticancer, immunotherapy, radiotherapy, biotheranostics, targeted therapy, photothermal, and photodynamic. Further, different imaging and diagnostics using nanocrystals are mentioned, including magnetic resonance imaging (MRI), computed tomography (CT), biosensing, and luminescence. Finally, the limitations and potential solutions of nanocrystals in the field of cancer theranostics are also discussed.
