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Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more.
Table des matières
Preface - Autophagy: An old mechanism with new challenges ahead
Aitziber Buqué and Lorenzo Galluzzi
1. Nucleophagy mediators and mechanisms
Margarita-Elena Papandreou and Nektarios Tavernarakis
2. Scaffold proteins in bulk and selective autophagy
Christopher Eickhorst, Mariya Licheva and Claudine Kraft
3. A global view of the miRNA-mitophagy connexion
Flavie Strappazzon
4. Crosstalk between autophagy and apoptosis: Mechanisms and therapeutic implications
Andrew Thorburn
5. Autophagy in immunity
Christian Münz
6. Autophagy in cardiovascular health and disease
Mahmoud Abdellatif, Senka Ljubojevic-Holzer, Frank Madeo and Simon Sedej
7. Autophagy in kidney disease: Advances and therapeutic potential
Divya Bhatia and Mary E. Choi
8. Autophagy in chronic lung disease
Alexandra C. Racanelli, Augustine M.K. Choi and Mary E. Choi
9. Autophagy contribution to motor neuron disease pathology
Natalia Rodríguez-Muela
10. Strategies employed by viruses to manipulate autophagy
Nilima Dinesh Kumar, Jolanda M. Smit and Fulvio Reggiori
11. Crinophagy mechanisms and its potential role in human health and disease
Tamás Csizmadia and Gábor Juhász
12. Autophagy role in environmental pollutants exposure
Gemma G. Martínez-García and Guillermo Mariño
13. Genetic defects of autophagy linked to disease
Milana Fraiberg and Zvulun Elazar
14. C. elegans to model autophagy-related human disorders
Shi Q. Wong, Anita V. Kumar, Joslyn Mills and Louis R. Lapierre
15. Drosophila as a model to understand autophagy deregulation in human disorders
Donna Denton, Louise O'Keefe and Sharad Kumar
