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G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes.
Table des matières
Preface
Arun K. Shukla
1. Computational and experimental approaches to probe GPCR activation and signaling
Paulina Dragan, Alessandro Atzei, Swapnil Ganesh Sanmukh and Dorota Latek
2. Adrenergic receptors in breast cancer
Cecilia Pérez Piñero, Ezequiel Mariano Rivero, Lucía Gargiulo, María Sol Rodríguez, Carlos David Bruque, Ariana Bruzzone and Isabel Alicia Lüthy
3. Tools for adapting to a complex habitat: G-protein coupled receptors in Trichoderma
Monika Schmoll and Wolfgang Hinterdobler
4. Targeting G protein-coupled receptors for alleviating neuropathic pain
Poonam Kumari, Anubhav Yadav, Monika Patel and Prem N. Yadav
5. Crosstalk between neurons and glia through G-protein coupled receptors: Insights from Caenorhabditis elegans
Pratima Pandey, Gazaldeep Kaur and Kavita Babu
6. Cardiovascular GPCR regulation by regulator of G protein signaling proteins
Anastasios Lymperopoulos, Malka S. Suster and Jordana I. Borges
7. The interaction, mechanism and function of GPR158-RGS7 cross-talk
Shradha Darira and Laurie P. Sutton
8. Taste GPCRs and their ligands
Nitzan Dubovski, Fabrizio Fierro, Eitan Margulis, Yaron Ben Shoshan-Galeczki, Lior Peri and Masha Y. Niv
9. Palmitoylation and G-protein coupled receptors
Georges Chaloub and Peter J. McCormick
