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Over the past 50 years, more than 20,000 natural compounds have been identified in the marine environment, with an increasing focus on marine metabolites as potential sources for developing effective therapeutic agents. The field of marine drug discovery has seen remarkable growth in recent years, with numerous marine-derived therapeutic candidates in various stages of clinical trials or awaiting approval. The ocean is a potential source of natural products with diverse pharmacological properties, including antimicrobial, anticancer, antiviral, antioxidative, and anti-inflammatory activities. However, commercializing marine natural products has been challenging due to low yields and specificity of specialized (secondary) metabolites.
Marine Specialized (Secondary) Metabolites and their Diverse Applications provides a broad overview of marine specialized metabolites and their potential in various industries. With comprehensive coverage, relevance to current trends, interdisciplinary approach, and practical applications, this book includes specific compounds or organisms, with a particular focus on addressing the challenges and limitations associated with them.
Table des matières
Part I - Chemistry and biochemistry of marine specialized metabolites1. Phenolic compounds and their halogenated derivatives
2. Terpenoids
3. Alkaloids
4. Sterols
5. Saccharide derivatives
6. Peptides
Part II - Application of marine specialized metabolites7. Marine secondary metabolites; in the long haul fight against cancer
8. Marine secondary metabolites in oxidative stress are promising
9. Promoting marine specialized metabolites against inflammation
10. Marine neutraceuticals; a solution for digestive tract health
11. Future prospects of marine resources in fighting diabetics
12. Advances and prospects in the field of cosmeceuticals with marine resources
13. Marine environment as a wonderful source over viral infections
14. Reverse aging is possible with marine resources
15. How to implement marine secondary metabolites in obesity struggle
16. Antimicrobial properties of marine specialized metabolites
Part III - Marine organisms as a natural product resource and beyond17. Marine secondary metabolites as a natural product resource
18. Contributions of marine secondary metabolites to medicinal chemistry
19. Blue-bioeconomy; marine specialized metabolites at the forefront
20. Marine secondary metabolites; an underexplored subject in metabolomics
21. Advances in marine secondary metabolite based metabolmics
A propos de l'auteur
Dr. Thilina U. Jayawardena is a scientist/postdoctoral fellow at the University of Alberta in Canada. He earned his BSc in Chemistry from the University of Colombo and his MSc and PhD in Marine Natural Sciences from Jeju National University in South Korea, focusing on medicinal and natural product chemistry. Dr. Jayawardena's research interests include natural product chemistry, with a focus on specialized metabolites. He co-led several book publications, including Elsevier’s forthcoming Marine Specialized (secondary) Metabolites and Their Diverse Applications.
Dr. Asanka Sanjeewa is Senior Lecturer at the University of Sri Jayewardenepura. He obtained his MSc and PhD in Marine Bioresource Technology at Jeju National University in South Korea, and he conducted his post-doctoral research in the Marine Bioresource Technology Laboratory of the Department of Marine Life Sciences at the School of Marine Biomedical Science at Jeju National University in South Korea. Dr. Sanjeewa's primary research interests focus on utilizing marine bioresources to develop functional products, such as nutraceuticals, cosmeceuticals, and functional foods. He co-led several book publications, including Elsevier’s forthcoming Marine Specialized (secondary) Metabolites and Their Diverse Applications.
