SYNTHESIS OF BENZO [D] IMIDAZOLE SUBSTITUTED DERIVATIVES - EVALUATION OF IN VITRO ANTI-TUBERCULAR ACTIVITY.. DE

In this present work, different benzimidazole derivatives were synthesised by conventional method and it was optimised by distinct melting point, infra-red spectroscopy and UV absorbance. All the synthesised compounds showed good antimicrobial activity and further it was scrutinized for anti-tubercular activity where the compounds 2 and 3 showed good activity against H37Rv strain whereas compound 1 showed moderate activity. So these compounds can be further subjected to drug designing and evaluated by computational studies to yield excellent activity.

A propos de l'auteur

O Sr. Ahamed Mueen Mubeen completou a sua Licenciatura UG (B.Pharm) na Universidade SRM e a Licenciatura PG ( M.Pharm) na Faculdade de Medicina de Madurai. Actualmente está a fazer o seu trabalho como Professor Assistente no Swamy Vivekanandha College of Pharmacy, Elayampalayam Tiruchengode, Tamilnadu-637205, Índia. 

Détails du produit

• Auteurs: Vasuki K, Ahamed Mueen Mubeen
• Edition: LAP Lambert Academic Publishing
• Langues: Anglais
• Format d'édition: Livre de poche
• Sortie: 01.01.2022
• EAN: 9786204978987
• ISBN: 9786204978987
• Pages: 60
• Catégorie: Sciences naturelles, médecine, informatique, technique > Médecine > Pharmacie