Nanomaterials in Clinical Therapeutics - Synthesis and Applications

NANOMATERIALS IN CLINICAL THERAPEUTICS
 
In this rapidly developing field, the book focuses on the practical elements of nanomaterial creation, characterization, and development, as well as their usage in clinical research.
 
Nanotechnology-based applications is a rapidly growing field encompassing a diverse range of disciplines that impact our daily lives. Nanotechnology is being used to carry out large-scale reactions in practically every field of biotechnology and healthcare. The incredible progress being made in these applications is particularly true for the healthcare sector, where they are used in cancer detection and treatment, medical implants, tissue engineering, and so forth. Expansions in this discipline are expected to continue in the future, resulting in the creation of a variety of life-saving medical technology and treatment procedures.
 
The primary goal of this book is to disseminate information on nanotechnology's applications in the biological sciences. A broad array of nanotechnological approaches utilized in different biological applications are highlighted in the book's 17 chapters, including the employment of nanotechnology in drug delivery. The first three chapters provide an overview of the history and principles of nanotechnology. The synthesis, characterization, and applications of nanomaterials are covered in the next 10 chapters. The last four chapters discuss the use of nanomaterials in clinical research.
 
Audience
The book will be useful for researchers and graduate students in the many areas of science such as biomedicine, environmental biotechnology, bioprocess engineering, renewable energy, chemical engineering, nanotechnology, biotechnology, microbiology, etc.

Table des matières

Preface xix
 
Part 1: History and Basic Principles of Nanotechnology 1
 
1 Introduction to Nanotechnology 3
Rekha Sharma, Kritika S. Sharma and Dinesh Kumar
 
1.1 Introduction 4
 
1.2 Nanoscale Materials: Importance 5
 
1.3 Nanotechnology: Historical Advances 8
 
1.4 Nanofabrication Methods in Nanotechnology 9
 
1.4.1 Top-Down Method 10
 
1.4.2 Bottom-Up Method 11
 
1.5 Carbon Nanoallotropes 13
 
1.5.1 Fullerene 13
 
1.5.2 Carbon Nanotubes 14
 
1.5.3 Graphene 15
 
1.6 Classification of the Nanomaterials 16
 
1.6.1 Based on Dimensions 16
 
1.6.2 Based on the Structural Configuration 17
 
1.7 Applications of Nanotechnology 18
 
1.7.1 Chip-Based Plasmonic Sensors 18
 
1.7.2 Nanoparticle-Based Colorimetric Sensors 20
 
1.7.3 Colloidal Nanoparticle-Based Plasmonic Sensors 21
 
1.8 Conclusions and Future Perspectives 23
 
Acknowledgment 23
 
References 24
 
2 Functional Principal of Nanotechnology in Clinical Research 33
Kalyanee Bera, Biva Ghosh and Mainak Mukhopadhyay
 
2.1 Introduction 34
 
2.2 Nanoparticles 36
 
2.3 Carbon-Based Nanoparticles 37
 
2.4 Metal Nanoparticles 37
 
2.4.1 Gold Nanoparticles 38
 
2.4.2 Silver Nanoparticles 39
 
2.4.3 Zinc Nanoparticles 39
 
2.5 Magnetic Nanoparticles 40
 
2.6 Ceramic Nanoparticles 41
 
2.7 Lipid Nanoparticles 41
 
2.8 Polymeric Nanoparticles (Nanoparticles Made of Polymers) 42
 
2.8.1 Synthetic 43
 
2.8.2 Natural 43
 
2.9 Hydrogel 44
 
2.10 Nanofibers 45
 
2.11 Nanocomposites 45
 
2.12 Nanotechnologies for Clinical Laboratory Diagnosis 46
 
2.12.1 Nanotechnology-Based Biochips and Microarrays 46
 
2.12.2 Protein Microarrays/Chips 47
 
2.12.3 Nanobiosensors 48
 
2.12.4 PEBBLE Nanosensors (Probes Encapsulated by Biologically Localized Embedding) 48
 
2.12.5 Quantum Dots 48
 
2.12.6 Fluorescence Microscopy for Chromosomal Changes 49
 
2.12.7 Nanobarcodes 49
 
2.12.8 Protein Biobarcode Assay 50
 
2.12.9 Cantilever Arrays 50
 
2.12.10 DNA-Protein and Nanoparticles Conjugates 51
 
2.12.11 Resonance Light Scattering Technology 52
 
2.12.12 Method of Colorimetric DNA Detection 52
 
2.12.13 Upcoming Phosphor Technology Based on Nanoparticles 53
 
2.13 Clinical Uses of Nanotechnology 53
 
2.13.1 Application of Nanocrystals in Immunohistochemistry 54
 
2.13.2 Detection of Illness Biomarkers 54
 
2.13.3 Disease Gene Detection 54
 
2.13.4 Detection of Microorganisms 55
 
2.13.5 Dental Nanotechnology 55
 
2.14 Nanofilm Applications 56
 
2.15 Nanomedicine Implementation 57
 
2.16 Future Prospects 58
 
2.17 Conclusion 58
 
References 59
 
3 Application of Nanotechnology in Clinical Research: Present and Future Prospects 75
Mansi Sharma, Pragati Chauhan, Rekha Sharma and Dinesh Kumar
 
3.1 Introduction 76
 
3.2 Scope of Nanotechnology in Clinical Research 77
 
3.3 Classification 78
 
3.3.1 Nanomaterials 78
 
3.3.1.1 Nanocrystal 80
 
3.3.1.2 Nanostructures 81
 
3.3.2 Nanodevices 89
 
3.4 Applications of Nanotechnology 91
 
3.4.1 Drug Delivery 93
 
3.4.2 Cancer Treatment 93
 
3.4.3 Gene Therapy 95
 
3.4.4 Tissue Engineering 95
 
3.4.5 Wound Treatment 96
 
3.4.6 Visualization 96
 
3.4.7 Tuberculosis Treatment 97
 
3.4.8 In

A propos de l'auteur

Mainak Mukhopadhyay, PhD, is an assistant professor in the Department of Biotechnology, JIS University, Kolkata, India. He obtained his PhD from the Indian Institute of Technology in Kharagpur, India in 2014. His research interests include enzymology, nanobiotechnology, and biomass conversion technology. He was awarded Petrotech Research Fellowship in 2008. In 2016 he was awarded the Early Career Research Award from DST-SERB. He has co-authored 15 peer-reviewed papers and three review papers, edited one book and 15 book chapters, and filed three patents.
Arindam Kuila is an assistant professor at the Department of Bioscience & Biotechnology, Banasthali Vidyapith, Rajasthan, India. Previously, he worked as a research associate at Hindustan Petroleum Green R&D Centre, Bangalore, India. He gained his PhD from the Agricultural & Food Engineering Department, Indian Institute of Technology Kharagpur, India in 2013 in the area of lignocellulosic biofuel production. He has co-authored 18 peer-reviewed research papers and seven review papers, edited four books and eight book chapters, and filed five patents.

Résumé

NANOMATERIALS IN CLINICAL THERAPEUTICS

In this rapidly developing field, the book focuses on the practical elements of nanomaterial creation, characterization, and development, as well as their usage in clinical research.

Nanotechnology-based applications is a rapidly growing field encompassing a diverse range of disciplines that impact our daily lives. Nanotechnology is being used to carry out large-scale reactions in practically every field of biotechnology and healthcare. The incredible progress being made in these applications is particularly true for the healthcare sector, where they are used in cancer detection and treatment, medical implants, tissue engineering, and so forth. Expansions in this discipline are expected to continue in the future, resulting in the creation of a variety of life-saving medical technology and treatment procedures.

The primary goal of this book is to disseminate information on nanotechnology's applications in the biological sciences. A broad array of nanotechnological approaches utilized in different biological applications are highlighted in the book's 17 chapters, including the employment of nanotechnology in drug delivery. The first three chapters provide an overview of the history and principles of nanotechnology. The synthesis, characterization, and applications of nanomaterials are covered in the next 10 chapters. The last four chapters discuss the use of nanomaterials in clinical research.

Audience
The book will be useful for researchers and graduate students in the many areas of science such as biomedicine, environmental biotechnology, bioprocess engineering, renewable energy, chemical engineering, nanotechnology, biotechnology, microbiology, etc.

Détails du produit

• Auteurs: Arindam Kuila, Mukhopadhyay, Mainak Mukhopadhyay, Mainak Kuila Mukhopadhyay
• Collaboration: Kuila (Editeur), Arindam Kuila (Editeur), Kuila Arindam (Editeur), Mainak Mukhopadhyay (Editeur)
• Edition: Wiley, John and Sons Ltd
• Langues: Anglais
• Format d'édition: Livre Relié
• Sortie: 30.11.2022
• EAN: 9781119857235
• ISBN: 978-1-119-85723-5
• Pages: 544
• Catégories: Sciences naturelles, médecine, informatique, technique > Chimie > Autres; Nanotechnologie, Medizin, Biomaterial, Nanotechnology, Biomedical engineering, Biomaterials, Nanomaterialien, Nanomaterials, Medical Science, Nanomaterial, Biomedizintechnik, Klinische Pharmakologie u. Therapie, Clinical Pharmacology & Therapeutics, Biomaterialien