Coordinating Organismal Physiology Through the Unfolded Protein Response

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.

Table des matières

Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response.- Cell Non-Autonomous UPR^ER Signaling.- The unfolded protein response in the immune cell development: Putting the caretaker in the driving seat.- Mitochondria associated membranes and ER stress.- Coordinating Organismal Metabolism during Protein Misfolding in the ER Through the Unfolded Protein Response.- ER stress and neurodegenerative disease: a cause or effect relationship?- Driving cancer tumorigenesis and metastasis through UPR signaling.- ER Protein Quality Control and the Unfolded Protein Response in the Heart.

A propos de l'auteur

R. Luke Wiseman

Associate Professor
Department of Molecular Medicine
The Scripps Research Institute MEM 220
La Jolla, CA 92037, USA

Phone: [phone]

Email: [e-mail]

Cole M. Haynes
Associate Professor
University of Massachusetts Medical School
Worcester, MA 01605, USA
Email:[e-mail]

Résumé

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.

Détails du produit

• Collaboration: Cole M. Haynes (Editeur), Luke Wiseman (Editeur), R Luke Wiseman (Editeur), M Haynes (Editeur), M Haynes (Editeur), R. Luke Wiseman (Editeur)
• Edition: Springer, Berlin
• Langues: Anglais
• Format d'édition: Livre de poche
• Sortie: 01.01.2018
• EAN: 9783030087234
• ISBN: 978-3-0-3008723-4
• Pages: 213
• Dimensions: 155 mm x 12 mm x 235 mm
• Poids: 349 g
• Illustrations: VII, 213 p.
• Thème: Current Topics in Microbiology and Immunology
• Catégories: Sciences naturelles, médecine, informatique, technique > Médecine > Spécialités non cliniques; Physiologie, Onkologie, B, Neurowissenschaften, Krankheiten und Störungen, Immunology, HUMAN PHYSIOLOGY, PHYSIOLOGY, INTERNAL MEDICINE, Neuroscience, Oncology, Infectious & contagious diseases, Neurosciences, infectious diseases, Biomedical and Life Sciences, Cancer Research, Biomedical Research, Diseases and disorders