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This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.
Table des matières
User's Guide to the Selection of Viral Vectors for Optogenetic Studies.- Cell Type-Specific Targeting Strategies for Optogenetics.- Molecular Engineering of Channelrhodopsis for Enhanced Control over the Nervous System.- Optogenetic Control of Intracellular Signaling: Class II Opsins.- Optogenetics in Stem Cell Research: Focus on the Central Nervous System.- Optogenetic Applications in the Nematode Caenorhabditis elegans.- Optogenetic Interpellation of Behavior Employing Unrestrained Zebrafish Larvae.- Combining Optogenetics with MEA, Depth-Resolved LFPs and Assessing the Scope of Optogenetic Network Modulation.- Concepts of All-Optical Physiology.- Two-Photon Optogenetics by Computer-Generated Holography.- Optophysiology and Behavior in Rodents and Non-Human Primates.- Employing Optogenetics in Memory Research.- Towards Opto-Magnetic Physiology: Concepts and Pitfalls of ofMRI.- Optogenetics: Lighting a Path from the Laboratory to the Clinic.
Résumé
This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.
