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Informationen zum Autor Ather Munner, MD, is assistant professor of psychiatry at the Islamic International Medical College, Riphah International University, Islamabad. He has published papers in numerous journals, and is a member of the Pakistan Psychiatric Society and the European Psychiatric Association. Klappentext Mood Disorders: Practical Issues in Diagnosis and Management provides cutting edge knowledge about the diagnosis and treatment of principal mood disorders, namely major depressive disorder and bipolar disorder. Covering diagnosis, differentiating features, and illness course and trajectories of principal mood disorders, Dr. Ather Muneer provides essential information in a succinct and practical manner, while highlighting significant new findings in the area. This book will help a broad range of mental health professionals better treat the millions of people with mood disorders across the globe. Zusammenfassung This book covers diagnosis, differentiating features, and illness course and trajectories of principal mood disorders, namely major depressive disorder and bipolar disorder. The book provides essential information on mood disorders in a succinct and practical manner, while highlighting significant new findings in the area. Inhaltsverzeichnis Table of Contents Chapter 1: Major Depressive Disorder and Bipolar Disorder Introduction Signs and Symptoms Diagnosis of Mood Disorders Major Depressive Disorder Bipolar Disorder Seasonal Affective Disorder (SAD) Conclusion Chapter 2: Major Mood Disorders: Differentiating Features Introduction Allostatic Load Model of Mood Disorders Mood Disorders as Systemic Ailments Differentiating Features of Unipolar and Bipolar Depression Affective Ailments as Spectrum Disorders Psychometric Scales How to Differentiate Between Unipolar and Bipolar Depression? Catatonic Symptoms of Mood Disorders Conclusion Chapter 3: Cormorbidity in Mood Disorders Introduction The Relation Between Mood Disorders and Inflammatory Comorbidity Mechanisms Linking Immune-Inflammatory Imbalance to GMC in Mood Disorders Therapeutic Considerations Conclusion Chapter 4: Etiology- The Role of Epigenetics Introduction The Relationship Between Mood Disorders and Inflammation The Biological Mechanisms Linking Mood Disorders and Inflammation Neuronal Plasticity Childhood Abuse and Mood Disorders The Link Between Childhood Trauma and Inflammation Childhood Trauma and Neuronal Plasticity The Epigenetic Link Future Directions Conclusion Chapter 5: Neurobiology of Mood Disorders- The Circadian Connection Introduction Mood Disorders and the Circadian System The Neurobiology of the Circadian System Conclusion Chapter 6: Pathogenesis of Mood Disorders- The Neuroinflammatory Hypothesis Introduction Neuroinflammation- The Role of Cytokines Inflammation, Kynurenines and Mood Disorders Purported Model of Depression Oxidative Stress Conclusion Chapter 7: Mood Disorders- Staging and Neuroprogression Introduction Developmental Trajectory and Clinical Heterogeneity of Mood Disorders Neuroprogression as the Basis for Staging Mood Disorders Allostatic Load and Neuroprogression Biomarkers of Mood Disorders Staging Models of BD Staging Model for MDD Therapeutic Implications of Staging Limitations of the Staging Models Conclusion Chapter 8: The Management of Treatment Resistant Depression- Monoamines and Beyond Introduction Switching or Combining 1st Line Antidepressants for TRD Combining Atypical Antipsychotics with Standard Antidepressants Voritoxetine in TRD Targeting Other Pathways in TRD Concl...
