Introduction to Randomized Controlled Clinical Trials

Table des matières

What is a Randomized Controlled Trial? Bias. How Many Patients Do I Need? Methods of Allocation. Assessment, Blinding and Placebos. Analysis of Results. Further Analysis: Binary and Survival Data. Monitoring Accumulating Data. Subgroups and Multiple Outcomes. Protocols and Protocol Deviations. Some Special Designs: Crossovers, Equivalence and Clusters. Meta-Analyses of Clinical Trials. Further Reading. Solutions to Exercises. References.

A propos de l'auteur

John N.S. Matthews

Résumé

Focusing on the important role that statistical methods play in the analysis of the data collected as well as in the overall clinical trial process, this title provides an introduction to clinical trials. It features examples, exercises, and material on binary outcomes and survival analysis. It features various real examples taken from The Lancet.

Détails du produit

• Auteurs: Bradley. P. Carlin, John N. S. Matthews, John N.S. Matthews, John N.s. (The University of Newcastle Matthews
• Collaboration: Bradley. P. Carlin (Editeur de la série), Chris Chatfield (Editeur de la série), Martin A. Tanner (Editeur de la série)
• Edition: Taylor & Francis Ltd.
• Langues: Anglais
• Format d'édition: Livre Relié
• Sortie: 31.12.2017
• EAN: 9781138469501
• ISBN: 978-1-138-46950-1
• Pages: 302
• Thème: Chapman & Hall/CRC Texts in Statistical Science
• Catégories: Sciences naturelles, médecine, informatique, technique > Médecine; MATHEMATICS / Probability & Statistics / General, MEDICAL / Pharmacology, Biology, life sciences, Probability & statistics, Pharmaceutical technology, Probability and statistics, Clinical Trials, Pharmaceutical chemistry and technology