Molecular & Cellular Targets for Anti-Epileptic Drugs

A new phase of anti-epileptic drugs (AEDs) investigation has begun in which new drugs can be designed to target specific epileptogenic mechanisms. A rational approach to therapy today requires not only a full awareness of phamacokinetics of AEDs but also a thorough knowledge of their molecular targets and of their influence on excitatory and inhibitory mechanisms in the brain. This book provides a multi-author systematic look at this subject, from neurobiological bases to clinical applications. It includes four sections dealing with fundamental aspects of cortical excitability, models of epileptic disorders, targets for anti-epileptic drugs and rational approaches to therapy. Each chapter provides a review of a specific topic prepared by well known scientists active in the field, introducing their most recent results in a concise and comprehensive form.

Détails du produit

• Collaboration: G Avanzini (Editeur), G. Avanzini (Editeur), M. Avoli (Editeur), G Regesta (Editeur), M Avoli (Editeur), P Tanganelli (Editeur), G. Regesta (Editeur), P. Tanganelli (Editeur)
• Edition: John Libbey & Co
• Langues: Anglais
• Format d'édition: Livre de poche
• Sortie: 01.01.1997
• EAN: 9780861965540
• ISBN: 978-0-86196-554-0
• Pages: 266
• Dimensions: 180 mm x 249 mm x 20 mm
• Poids: 688 g
• Illustrations: Illustrations
• Thèmes: Current Problems in Epilepsy; Current problems in epilepsy
• Catégorie: Sciences naturelles, médecine, informatique, technique > Médecine > Spécialités cliniques