Fr. 239.00

AMP-activated Protein Kinase

Anglais · Livre Relié

Expédition généralement dans un délai de 6 à 7 semaines

Description

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AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes.

This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.

Table des matières

Part I: AMPK in health.- Structure and Regulation of AMPK.- AMPK Regulation of Carbohydrate Metabolism.- AMPK Regulation of Lipid Metabolism.- AMPK Regulation of Protein Metabolism.- AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics.- AMPK Regulation of immunology.- AMPK and Stem Cells.- Part II: AMPK in the diseases.- AMPK in metabolic diseases.- AMPK in neurodegenerative diseases.- AMPK in cardiovascular diseases.- AMPK in cancer.- AMPK in aging.- AMPK in musculoskeletal diseases and pain.- AMPK in pathogens.- Part III: Pharmacology of AMPK.- Metformin, new drugs and AMPK.- Small molecules and AMPK.- Nutraceutical compounds and AMPK.- Part IV: Methods of study in AMPK.- Animal models.- In vitro study methods.

A propos de l'auteur

Mario D Cordero is Research Associate at the University of Sevilla, Laboratory of Biological Research. He studies the role of AMPK in the metabolic abnormalities of the central nervous system in psychiatric diseases, and the implication of AMPK in the mechanism of pain and inflammation. He is also involved in drug trials using AMPK activators in rare diseases.
 
 
Benoit Viollet leads a research team at the Institut Cochin, Paris, which studies the physiological role of AMPK in cellular energy balance and the integrated stress response such as exercise, as well as nutrient and hormonal signals. The work includes studies of the therapeutic opportunity of AMPK in metabolic abnormalities associated with type 2 diabetes and obesity.
 

Résumé

AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes.
This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease. 

Détails du produit

Collaboration Mario D. Cordero (Editeur), Mari D Cordero (Editeur), Mario D Cordero (Editeur), VIOLLET (Editeur), Viollet (Editeur), Benoit Viollet (Editeur)
Edition Springer, Berlin
 
Langues Anglais
Format d'édition Livre Relié
Sortie 01.01.2016
 
EAN 9783319435879
ISBN 978-3-31-943587-9
Pages 523
Dimensions 164 mm x 37 mm x 242 mm
Poids 972 g
Illustrations X, 523 p. 55 illus., 42 illus. in color.
Thèmes Experientia Supplementum
Experientia Supplementum
Catégories Sciences naturelles, médecine, informatique, technique > Biologie

B, Krankheiten und Störungen, Medizinische Chemie, Pharmazeutische Chemie, Diseases, HUMAN PHYSIOLOGY, METABOLISM, biochemistry, Biomedical and Life Sciences, Medical Biochemistry, Diseases and disorders, Metabolic Diseases

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