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Informationen zum Autor Professor Laurens Holmes Jr. was trained in internal medicine, specializing in immunology and infectious diseases prior to his expertise in epidemiology-with- biostatistics. He is an advocate of reality in modeling of epidemiologic, clinical and biomedical research data, consequential epidemiology, as well as explanatory ecologic model in understanding the complex etiologies of health and disease. Over the past two decades, Dr. Holmes had been working in cancer epidemiology, control & prevention with substantial publication on hormonally-related malignancies mainly prostate, thyroid, cervical, and testicular. Other areas where his focus had been during the last fifteen years include pediatric malignancy namely ALL, AML, lymphoma, brain and CNS. His involvement in chronic disease epidemiology, control and prevention includes signal amplification and stratification in risk modeling and health disparities in hypertension, and diabetes mellitus with large legacy (preexisting US National Health Statistics Center) data. Professor Holmes is a pioneer of health disparities epidemiology where he presents on disentangling race in epidemiologic studies by re-considering the biologic,bio-molecular, genetic, epigenetic determinants of disease incidence, prevalence, morbidity, prognosis, severity and mortality. Klappentext This book provides practical knowledge to clinicians and biomedical researchers using biological and biochemical specimen in order to understand health and disease processes at cellular, clinical, and population levels. Concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics. Zusammenfassung This book provides practical knowledge to clinicians and biomedical researchers using biological and biochemical specimen in order to understand health and disease processes at cellular, clinical, and population levels. Concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics. Inhaltsverzeichnis Part I Chapter One Epidemiologic Research Conceptualization Chapter Two Epidemiologic Proposal Development & Protocol Chapter Three Epidemiologic Research Challenge: Confounding, and Effect Measure Modifier Chapter Four Epidemiologic Case Ascertainment: Disease Screening & Diagnosis Part II Epidemiologic Methods & Concepts Chapter Five Epidemiologic Methods and the Measures of Disease Occurrence and Association Chapter Six Epidemiologic Study Designs : Overview Chapter Seven Ecologic Studies: Design, Conduct & Interpretation Chapter Eight Case-Control Studies: Design, Conduct & Interpretation Chapter Nine Cross-sectional Studies: Design, Conduct & Interpretation Chapter Ten Cohort Studies: Design, Conduct & Interpretation Chapter Eleven Clinical Trials (Experimental Designs) Chapter Twelve Epidemiologic Causal Inference in Clinical and Quantitative Evidence Synthesis Part III Perspectives, Challenges and Future of Epidemiology Chapter Thirteen Perspectives and Challenges in Epidemiology Chapter Fourteen Role of Epidemiology in Health and Healthcare Policy Chapter Fifteen Consequentialist Epidemiology in Clinical & Translational Research ...
