DNA Repair and Human Disease

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

Table des matières

Human Premature Aging Disorders and Dysfunction of DNA Repair.- DNA Repair Aspects for RecQ Helicase Disorders.- Trichothiodystrophy.- Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair.- Radiosensitivity of Cells Derived from Down Syndrome Patients.- The Fanconi Anemia/BRCA Pathway.- Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators?.- Mechanisms of DNA Damage and Repair in Alzheimer Disease.- Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells.- Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients.

Résumé

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

Détails du produit

• Auteurs: Adayabalam Balajee
• Edition: Springer, Berlin
• Langues: Anglais
• Format d'édition: Livre de poche
• Sortie: 01.01.2014
• EAN: 9781489998996
• ISBN: 978-1-4899-9899-6
• Pages: 150
• Dimensions: 155 mm x 9 mm x 235 mm
• Poids: 260 g
• Illustrations: XII, 150 p.
• Thèmes: Medical Intelligence Unit; Medical Intelligence Unit
• Catégories: Sciences naturelles, médecine, informatique, technique > Médecine > Spécialités cliniques; Protein, B, Zellbiologie (Zytologie), Mikrobiologie und Virologie, Medical microbiology & virology, Human Genetics, Biomedical and Life Sciences, Medical Genetics, Cellular biology (cytology), Medical Microbiology, Cell Biology