Apoptosis related proteins p53 and Bcl-2 in hepatocellular carcinoma

Hepatitis B virus and hepatitis C virus may be involved in hepatocarcinogenesis in patients with HCC. These viral infections may be responsible, at least in a part, for the mutational change in the p53 gene and may affect the expression of the Bcl-2 protein in HCC patients. p53 and Bcl-2 proteins overexpression was detected in serum and tissues in HCC patients positive for hepatitis B or C or both and this overexpression was more frequently associated with HBV infection than HCV infection.

A propos de l'auteur

Dr. Entsar A. Saad is Associate Professor of Biochemistry at Damietta University (Egypt). She completed her under and graduate studies with a Ph.D. from Mansoura University (Egypt). She is a member of the Egyptian Society of Biochemistry and Molecular Biology.

Détails du produit

• Auteurs: Hoda El-Emshaty, Entsa Saad, Entsar Saad, El-Shaha Toson, El-Shahat Toson
• Edition: LAP Lambert Academic Publishing
• Langues: Anglais, Allemand
• Format d'édition: Livre de poche
• Sortie: 01.01.2014
• EAN: 9783659611117
• ISBN: 978-3-659-61111-7
• Pages: 292
• Catégorie: Sciences naturelles, médecine, informatique, technique > Chimie > Autres