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This book provides insight into all important fields in bioinformatics including sequence analysis, expression analysis, structural biology, proteomics and network analysis. Many of the leading scientists in the field have contributed chapters to topics of which range from genome sequence determination and its analysis, to the analysis of transcripts and proteins with the final aim of gaining a deeper understanding of the complex networks cells must obey to in order to live. The book has been compiled for the increasing number of scientists and researchers working in bioinfomatics and genome analysis worldwide who would like not only to get an overview but who also enjoy reading about the latest results in this exciting field.
Table des matières
From the contents:
A. Reis: Human Genetics - Genotyping
G. van Heijne: Bioinformatics of Membrane Proteins
G. Kolesov, H.-W. Mewes, D. Frishman: SNAPping up Functionally Related Genes Based on Context Information
T. Werner: Promoter Analysis
R. Sharan, R. Elkon, R. Shamir: Cluster Analysis and its Applications to Gene Expression Data
N. Friedman, N. Kaminski: Statistical Methods for Analyzing Gene Expression Data for Cancer Research
W. Taylor: Structural Genomics
L. Brive, R. Abagyan: Computational Structural Proteomics
M. Gentzel, Th. Kocher, M. Wilm: Proteomics in Biological Research: The Challenge to Make Proteins Speak
V. Schächter: Construction and Prediction of Protein-Protein Interaction Maps
H.V. Westerhoff: Bioinformatics, Cellular Flows, and Simulation
J. van Helden, L. Wernisch, D. Gilbert, S. Wodak: Graph-based Analysis of Metabolic Networks
R. Gupta, L.J. Jensen, S. Brunak: Orphan Protein Function and its Relation to Glycosylation.
