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Zusatztext Anyone with even a passing interest in the topic (basic scientists, students, clinicians, social workers, patients, family members) will find something of interest and edification. This is exactly what the editors had in mind: a reference and resource on nervous system disorders associated with HIV. Informationen zum Autor Howard E. Gendelman, MD, Professor and Chair, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical CenterOmaha, NE. Igor Grant, MD, Distinguished Professor of Psychiatry, Director, HIV Neurobehavioral Research Program, University of California-San Diego, La Jolla, CA. Ian Paul Everall, MD, PhD, Professor of Psychiatry and Head of Department, University of Melbourne, Victoria, Australia.Howard S. Fox, MD, PhD, Professor, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE. Harris A. Gelbard, MD, PhD, Director of The Center for Neural Development and Disease, Professor of Neurology, Pediatrics, Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY. Stuart A. Lipton, MD, PhD, Professor and Scientific Director, Sanford-Burnham Medical Research Institute; Adjunct Professor of Neurosciences, University of California-San Diego; Adjunct Professor, The Salk Institute for Biological Studies and The Scripps Research Institute, La Jolla, CA. Susan Swindells, MBBS, Professor of Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE. Klappentext Fully updated and extensively illustrated this new edition covers each of neurological complications of AIDS. From basic science to clinical care and epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology, and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the HIV. Zusammenfassung Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral therapy (ART). Long-term resistance to ART, drug compliance, untoward drug side effects, a myriad of opportunistic infection, depression and other psychiatric disease manifestations, concomitant drug abuse, neuropathies, and an inability to clear viral reservoirs, explain, in large measure, disease progression and immune deterioration. These are associated with a number of psychiatric, muscle, nerve, infectious, as well as cognitive, behavioral, and motor disturbances seen in infected people. Fully updated from the previous two editions and replete with color images, The Neurology of AIDS, Third Edition covers each of these neurological complications and more with a focus on molecular and viral disease processes, cellular factors influencing viral replication therapeutic challenges, and the changing epidemiological patterns of disease. From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Inhaltsverzeichnis Section 1. HIV-1 Biology and Immunology 1.1. HIV-1 Biology, Michael Bukrinsky and Sergey Iordanskiy 1.2. HIV-1 Immunology, Sabita Roy, Subhash Dhawan, Shilpa Buch, and Krishnakumar Devadas 1.3 Chemokines, Richard J. Miller 1.4 Viral and host genetic factors, Christopher Power, Jennifer A. McCombe, Shaona Acharjee, and M. John Gill 1.5 Genetic Susceptibilities in neuroAIDS, Sunil K. Ahuja, Srinivas Mummidi, Jason F. Okulicz, Edwina J. Wright, and Weijing He Section 2. Innate and Cellular Immunity and Neurogenesis 2.1...
