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Part I: Social and Ethical Issues in Medicine 1. Approach to Medicine, the Patients and Medical Profession Medicine as a Learned & Human Profession, Lee Goldman and Dennis Ausiello 2. Bioethics in the Practice of Medicine, Ezekiel Emanuel 3. Care of Dying Patients and Their Families, J. Andrew Billings 4. Social and Economic Issues in Medicine, Steven Schroeder Part II: Principles of Evaluation and Management 5. Approach to the Patient: History and Physical Examination, David Simel 6. Interpretation of Data for Clinical Decisions, Thomas H. Lee 7. Applications and Limitations of Diagnostic Medical Imaging, David Avrin 8. Principles of Outcome Assessment, Albert W. Wu 9. Applications of Statistics, Catarina I. Kiefe Part III: Preventive and Environmental Medicine 10. Principles of Preventive Health Care, Albert Oberman 11. The Periodic Health Examination, David Atkins 12. Nutrition's Interface with Health and Disease, Douglas C. Heimburger 13. Physical Activity, Michael Pratt 14. Tobacco, Neal L. Benowitz 15. Violence and Injury, Elizabeth McLoughlin 16. Immunization, Walter A. Orenstein 17. Alcoholism and Alcohol Abuse and Dependence, Patrick O'Connor 18. Principles of Occupational and Environmental Medicine, Philip J. Landrigan 19. Radiation Injury, Arthur C. Upton 20. Chronic Poisoning: Trace Metals and Others, William O. Robertson and Thomas Martin Part IV: Aging and Geriatric Medicine 21. Epidemiology of Aging: Implications of the Aging, Linda Fried 22. Biology of Aging, George Martin 23. Approach to Common Clinical Sequelae of Aging, Kenneth Minaker 24. Uniary Incontinence, Joseph C. Ouslander 25. Neuropsychiatric Aspects of Aging, Sharon K. Inouye 26. Delirium and Other Mental Status Problems in the Older Patient, Sharon K. Inouye Part V: Clinical Pharmacology 27. Principles of Drug Therapy, Robert B. Diasio 28. Drug Allergy, James R. Bonner 29. Pain, Mitchell Max 30. Drug Abuse and Dependence, Jeffrey H. Samet 31. Glucocorticoids in Relation to Inflammatory Disease, Paul Katz 32. Prostaglandins, Aspirin, and Related Compounds, Garrett Fitzgerald 33. Antithrombotic Therapy, Jack Hirsh 34. Alternative Complementary and Alternative Medicine, Stephen Straus Part VI: Genetics 35. Principles of Genetics, Bruce Korf 36. Genetic Risk Assessment, Margretta R. Seashore 37. Inborn Errors of Metabolism, Louis J. Elsas II 38. Single Gene and Chromosomal Disorders, Judith Hall 39. The Inherited Basis of Common Diseases, David Altshuler 40. Gene Therapy, Paul N. Reynolds, Akseli Hemminki, and David T. Curiel Part VII: Principles of Immunology and Inflammation 41. The Innate and Adaptive Immune Systems, Cornelia M. Weyand and Jorg J. Goronzy 42. The Major Histocompatibility Complex and Disease Susceptibility, Robert Rich 43. Mechanisms of Immune Mediated Tissue Injury, Jane Salmon 44. Mechanisms of Inflammation and Tissue Repair, Gary Firestein and Shao-Lee Lin 45. Complement in Health and Disease, David R. Karp; V. Michael Holers Part VIII: Cardiovascular Disease 46. Approach to the Patient with Possible Cardiovascular Disease, Lee Goldman 47. Epidemiology of Cardiovascular Disease, Michael H. Criqui 48. Cardiac Function and Circulatory Control, Daniel Burkhoff and Myron L. Weisfeldt 49. Radiology of the Heart, Murray G. Baron 50. Cardiography, Nora Goldschlager 51. Echocardiography, Anthony N. DeMaria 52. Nuclear Cardiology and Computed Tomography, George A. Beller 53. Cardiovascular Magnetic Resonance Imaging, Warren J. Manning 54. Catheterization and Angiography, David P. Faxon 55. Pathophysiology Heart Failure: and Dignosis, Barry Massie 56. Management and Prognosis of Heart Failure, Milton Packer