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Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, geni tourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities,basic biology, and more.
Inhaltsverzeichnis
I. Basic Aspects of Oncogenes in Malignant Transformation.- 1. Oncogenes and proto-oncogenes: General concepts.- 2. Molecular biology: Concepts and techniques.- 3. The myc family of nuclear proto-oncogenes.- 4. The ras family of oncogenes.- 5. src-related protein tyrosine kinases.- 6. The epidermal growth factor receptor and its ligands.- 7. The platelet-derived growth factor system.- 8. Transforming growth factors-? and -? and their potential roles in neoplastic transformation.- II. Clinical Aspects of Oncogenes in Human Neoplasia.- 9. Oncogenes in human solid tumors.- 10. Oncogenes in human leukemias and lymphomas.- 11. Human retrovirus-associated malignancy.- 12. The human DNA tumor viruses: Human papilloma virus and Epstein-Barr virus.- 13. Molecular biology of the human retinoblastoma gene.- 14. Therapeutic applications of oncogenes.
Bericht
'This book contains several outstanding reviews and important perspectives in a field that seems to be changing every year. It is an important contribution that many people would find useful to review and have on their shelves.' Breast Cancer Research and Treatment 19 1991
