Ovarian Hyperstimulation Syndrome (OHSS) Free Clinic - An Algorithm for Change

The book presents a comprehensive guide to eliminating ovarian hyperstimulation syndrome (OHSS) from assisted reproduction. This first-of-its-kind volume unites global experts from Israel, India, Turkey, and Italy to deliver a step-by-step clinical algorithm for safer, patient-centered IVF.
The book explores OHSS from every angle pathophysiology, prediction, prevention, and rescue, while introducing cutting-edge strategies such as metformin use, luteal phase modifications, freeze-all protocols, and in-vitro maturation (IVM). It evaluates the relevance of HCG triggers and presents emerging pharmacological solutions that reshape modern stimulation practices.
Clinicians gain practical tools, visual aids, and evidence-based insights to minimize risk and maximize outcomes. The final chapter synthesizes two decades of research into a visionary protocol for OHSS-free IVF worldwide.
With contributions from renowned figures like Eitan Lunenfeld, Raoul Orvieto, Shahar Kol, Kemal Ozgur, and Andrea Borini, this book serves as both a hands-on manual and an authoritative reference for ART professionals committed to advancing reproductive medicine without compromise.

Inhaltsverzeichnis

1. Pathophysiology of OHSS Is it always iatrogenic?.- 2. Current concepts, etiopathology & staging of OHSS.- 3. Prediction & risk-factors of OHSS.- 4. Primary & Secondary OHSS.- 5. Role of counseling in an OHSS-free clinic.- 6. Role of ovarian markers in prevention of OHSS.- 7. Can newer biochemical markers prevent OHSS?.- 8. Role of ultrasound in the prediction & prevention of OHSS.- 9. Current status of metformin in OHSS prevention.- 10. Tweaking follicular phase stimulation protocols for prevention of OHSS.- 11. Luteal phase strategies to prevent OHSS.- 12. Interventional rescue strategies for unexpected OHSS.- 13. Is HCG trigger history?.- 14. The Role of Ultrasound in minimizing morbidity in OHSS.- 15. Is IVM still relevant for an OHSS free clinic?.-16. Newer drugs, interventions & strategies for an OHSS.- 17. Freeze-all for all is the way ahead.- 18. Is there an ideal stimulation protocol for an OHSS-free clinic?.

Über den Autor / die Autorin

Dr. Gautam Nand Allahbadia is Consultant Reproductive Medicine and Infertility at the Allahbadia Fertility Clinic, DHCC, Bourn Hall Fertility Clinic, Jumeirah and Ferticlinic Fertilization Centre, Sharjah, UAE. He is the founder and Mentor of Rotunda - The Center for Human Reproduction, an IVF Center at Wadala, India. He is a noted world authority on ultrasound-guided embryo transfers and one of the pioneers in third party reproduction in Southeast Asia. Dr. Allahbadia was responsible for India’s first trans-ethnic surrogate pregnancy involving a Chinese couple’s baby delivered by an unrelated Indian surrogate mother. Dr. Allahbadia is the Emeritus Editor of the Journal of Obstetrics & Gynecology of India and IVF Lite (Journal of Minimal Stimulation IVF). He cherishes over 150 peer-reviewed publications, 154 book chapters and 45 textbooks, the latest being a comprehensive text published by Jaypee Brothers Medical publications, entitled "Family Balancing with PGTA" in 2025, and is on the editorial board of several international journals. Dr. Allahbadia was elected as the Vice President of the World Association of Reproductive Medicine (WARM), headquartered in Rome, and “Mumbai’s Top Doc” for 2012 by a peer nomination process. He has a consultant “A” licensure with Dubai Health Authority (DHA) and was an expert with DHA interviewing new doctors applying for the DHA license to practice in the UAE between 2018-2022. You can read more about his work at www.gautamallahbadia.com.

Dr. Akanksha Allahbadia Gupta currently works at Sumitra Hospital, Noida, India. She has previously worked at the infertility clinic, Rotunda-The Center for Human Reproduction in Mumbai, India. She has worked in gynecological oncology as well as the women’s health departments in the Massachusetts General Hospital as part of her training with Harvard Medical School, Boston. She has completed her fellowship in minimal access surgery from the World Laparoscopy Hospital, Gurgaon, India. She is also a certified assessor for ART center accreditation as part of the quality and accreditation institute. She has been involved in over a thousand IVF procedures, managing a variety of cases including patients with high-risk pregnancies, multiple gestations, male factor infertility, endometriosis, multiple fibroids, mullerian anomalies, premature ovarian failure and recurrent pregnancy losses. She has won multiple prizes in paper and poster presentations at national level. She is also a co-author in many manuscripts contributed to internationally- acclaimed books and peer-reviewed Journals.

Dr. Swati Allahbadia is a Fertility Physician, Endoscopist and Obstetrician based in Mumbai, India and working in women’s health since the last thirty years. She did her graduate and postgraduate studies in medicine and gynecology from the Seth G S Medical College and King Edward Memorial (KEM) Hospital, Mumbai, India. She has been a Lecturer, Associate Professor and Unit Head at a Government Hospital in Mumbai. She got her training in endoscopy at the Ethicon Institute and as a holder of the Hargobind Fellowship, got trained in endoscopic microsurgery as well as robotic surgery in the United States. She holds Diplomas in Endoscopy and in Reproductive Medicine from Germany. Dr. Allahbadia currently manages Rotunda - The Center for Human Reproduction, Mumbai. At Rotunda, she has managed several cases including patients with multiple IVF failures, endometriosis, ovarian tumours, diminished ovarian reserve and recurrent pregnancy losses. She is attached to the Global, Raheja, Breach Candy and Wadia Hospitals in Mumbai.

Zusammenfassung

The book presents a comprehensive guide to eliminating ovarian hyperstimulation syndrome (OHSS) from assisted reproduction. This first-of-its-kind volume unites global experts from Israel, India, Turkey, and Italy to deliver a step-by-step clinical algorithm for safer, patient-centered IVF.
The book explores OHSS from every angle—pathophysiology, prediction, prevention, and rescue, while introducing cutting-edge strategies such as metformin use, luteal phase modifications, freeze-all protocols, and in-vitro maturation (IVM). It evaluates the relevance of HCG triggers and presents emerging pharmacological solutions that reshape modern stimulation practices.
Clinicians gain practical tools, visual aids, and evidence-based insights to minimize risk and maximize outcomes. The final chapter synthesizes two decades of research into a visionary protocol for OHSS-free IVF worldwide.
With contributions from renowned figures like Eitan Lunenfeld, Raoul Orvieto, Shahar Kol, Kemal Ozgur, and Andrea Borini, this book serves as both a hands-on manual and an authoritative reference for ART professionals committed to advancing reproductive medicine without compromise.

Produktdetails

• Mitarbeit: Gautam Nand Allahbadia (Herausgeber), Swati Allahbadia (Herausgeber), Akanksha Allahbadia Gupta (Herausgeber), Akanksha Allahbadia Gupta (Herausgeber)
• Verlag: Springer, Berlin
• Sprache: Englisch
• Produktform: Fester Einband
• Erscheint: 25.12.2025
• EAN: 9789819532889
• ISBN: 978-981-9532-88-9
• Seiten: 237
• Illustration: VI, 237 p. 22 illus., 21 illus. in color.
• Themen: Naturwissenschaften, Medizin, Informatik, Technik > Medizin > Klinische Fächer; Klinische und Innere Medizin, INTERNAL MEDICINE, Gynecology, Maternal and Child Health, Ovarian hyperstimulation syndrome, In vitro fertilization, Ideal Stimulation Protocol, Safe Stimulation, Prediction & Prevention of Complications in ART