Recent Advancement in Prodrugs

Prodrugs are said to be bioreversible derivatives which on biotransformation change into active pharmacophore. Prodrugs has been extensively studied amongst the drug design scientists for a wide range of applications. This book will cover the specific examples of prodrugs that overcomes drugs side-effects.

Inhaltsverzeichnis

Recent advancements in New drug design and development of prodrugs. Codrugs: Optimum use through prodrugs. Role of Prodrugs in Drug Design. Prodrugs for enhancement of lipophilicity. Lipidic Prodrugs for Drug Delivery: Opportunities and Challenges. The progress of prodrugs in drug solubility. Prodrugs for CNS drug delivery. Prodrugs for Cancer Treatment. Prodrugs in cancer nanomedicine and therapy. Nitroreductases in prodrug therapies. Prodrug approach using carboxylesterase: Different substrate specificities of human carboxylesterase isozymes. Mathematical models for ADME of prodrugs. Prodrug Approaches for Natural Products. Biotechnology based prodrug approach for cell-specific targeting: its theoretical basis and application.

Über den Autor / die Autorin

Kamal Shah, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, Pradeep Mishra

Zusammenfassung

Prodrugs are said to be bioreversible derivatives which on biotransformation change into active pharmacophore. Prodrugs has been extensively studied amongst the drug design scientists for a wide range of applications.  This book will cover the specific examples of prodrugs that overcomes drugs side-effects.

Produktdetails

• Autoren: Kamal Chauhan Shah
• Mitarbeit: Durgesh Nandini Chauhan (Herausgeber), Pradeep Mishra (Herausgeber), Kamal Shah (Herausgeber), Shah Kamal (Herausgeber), Nagendra Singh Chauhan (Herausgeber)
• Verlag: Taylor & Francis Ltd.
• Sprache: Englisch
• Produktform: Fester Einband
• Erschienen: 28.05.2020
• EAN: 9780367348366
• ISBN: 978-0-367-34836-6
• Seiten: 336
• Themen: Naturwissenschaften, Medizin, Informatik, Technik > Medizin > Pharmazie; Sachbuch > Natur, Technik > Naturwissenschaft; Medical research, SCIENCE / Chemistry / Industrial & Technical, SCIENCE / General, SCIENCE / Chemistry / General, MEDICAL / Pharmacology, SCIENCE / Chemistry / Physical & Theoretical, SCIENCE / Chemistry / Clinical, Pharmacology, Pharmaceutical technology, Pharmaceutical chemistry and technology