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Viruses: From Understanding to Investigation, Second Edition presents the definitions and unique characteristics of viruses. The book includes major topics such as virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions, and methods to study. In addition, the book assesses the connections between the aforementioned topics and provides an integrated approach and in-depth understanding of how viruses work. The new edition also provides an expanded methods chapter containing new information on deep sequencing for in virus identification, mathematical formulas to calculate titers and a description of quantitiative PCR for enumerating viruses. The vaccine chapter has been updated to include vaccine efficacy, mRNA vaccines and SARS-CoV-2 vaccine development. The viral pathogenesis chapter has been expanded to include mechanisms of virally induced cancers. Viral taxonomy sections have been updated and chapters revised to accommodate new virus family designations. New chapters include nucleocytoplasmic viruses (very large DNA viruses), replication of viroids and COVID-19/SARS-CoV-2.
Inhaltsverzeichnis
1. Introduction to animal viruses
2. Virus structure
3. Virus interactions with the cell
4. Methods to study viruses
5. Virus transmission and epidemiology
6. Immunity and resistance to viruses
7. Viral vaccines
8. Antiviral agents
9. Virus evolution and genetics
10. Viral pathogenesis
11. Introduction to RNA viruses
12. Family
Picornaviridae13. Family
Caliciviridae14. Family
Hepeviridae15. Family
Astroviridae16. Family
FlaviviridaeFamilies
Togaviridae and
Matonaviridae18. Family
Coronaviridae19. SARS-CoV-2/COVID-19
20. Family
Arteriviridae21. Family
Rhabdoviridae22. Family
Paramyxoviridae23. Family
Pneumoviridae24. Family
Filoviridae25. Family
Bornaviridae26. Family
Orthomyxoviridae27. Family
Hantaviridae28. Order Bunyavirales: Families
Peribunyaviridae,
Phenuiviridae, and
Nairoviridae
29. Family
Arenaviridae30. Family
Reoviridae31. Family
Birnaviridae32. Hepatitis delta virus
33. Introduction to DNA viruses
34. Family
Parvoviridae35. Other small DNA viruses
36. Family
Polyomaviridae37. Family
Papillomaviridae38. Family
Adenoviridae39. Family
Herpesviridae40. Family
Poxviridae41. Other large DNA viruses
42. Family
Retroviridae43. Replication and pathogenesis of human immunodeficiency virus
44. Family
Hepadnaviridae
Über den Autor / die Autorin
Susan Payne is an associate professor emeritus at Texas A&M University. Her primary research interests were molecular aspects of viral replication, pathogenesis and evolution. For many years her research focused on equine infectious anemia virus (EIAV), an equine retrovirus. She published extensively on genetic and antigenic variation and the molecular basis of EIAV pathogenesis. She also studied avian bornaviruses, negative strand RNA viruses that are the etiological agents of proventricular dilatation disease of parrots. Her long teaching career included courses for undergraduate and graduate students as well as participation in courses for medical and veterinary students. She was a member of the Bornavirus Study Group of the International Committee for Taxonomy of Viruses from 2014-2019.