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This is the first handbook on the whole field of stem cell research covering (1) molecular and cellular fundamentals, (2) clinical applications and (3) GMP processing. It provides a timely overview of the potential and plasticity of adult stem cells. With its focus on standardization and quality control of cell lines suited for processing and clinical trials, the book features novel therapeutic approaches that offer great promise for new ways of treating neural, hematological and cardiovascular diseases.The editors are leading international experts in adult stem cell research, and their successful networking in the US and Europe has resulted in a distinguished team of authors from around the world.
Inhaltsverzeichnis
STEM CELL BIOLOGY
Clinical Potentials of Stem Cells: Hype or Hope?
Alteration of Hematopoietic Stem Cell Fates by Chromatin-Modifying Agents
Increasing Impact of Micro RNAs in Stem Cell Biology and Medicine
STANDARDIZATION AND QUALITY ASSURANCE OF STEM CELL PREPARATIONS
Novel Strategies for the Acquisition of Hematopoietic Stem Cells
Pluripotent Stem Cells from Umbilical Cord Blood
Good Manufacturing Practices: Clinical-Scale Production of Mesenchymal Stem Cells
The Clonal Activity of Marked Hematopoietic Stem Cells
ON THE THRESHOLD TO CLINICAL APPLICATIONS
A Large Animal Non-injury Model for Study of Human Stem Cell Plasticity
Developmental Potential of Somatic Stem Cells Following Injection into Murine Blastocysts
Testing the Limits: The Potential of MAPC in Animal Models
Mesenchymal Stem Cells as Vehicles for Genetic Targeting of Tumors
CLINICAL TRIALS
Endothelial Progenitor Cells for Cardiac Regeneration
Stem Cells and Bypass Grafting for Myocardial and Vascular Regeneration
Adoptive Immunotherapy: Guidelines and Clinical Practice
Immune Escape and Suppression by Human Mesenchymal Stem Cells
Stem Cell Transplantation: The Basis for Successful Cellular Immunotherapy
Bericht
"This book presents a stimulating cross-section of current research and a vision of stem cell based therapies." ( Doody s Health Services )
