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This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools for new target generation , new approaches to cancer drug discovery through natural products based lead generation, and enabling technologies which leverage the unique attributes of natural products.
Inhaltsverzeichnis
Preface.- The Impact of Natural Products upon Cancer Chemotherapy.- Identification and development of vascular disrupting agents: Natural products that interfere with tumor growth.- Discodermolide: Past, Present and Future.- HDAC Inhibitors and Other Histone Modifying Natural Products as Emerging Anticancer Agents .- Natural Product Cytotoxins As Payloads For Antibody Drug Conjugates.- Natural Product Scaffolds in Cancer Therapy.- The Role of Genetic Engineering in Natural Product-based Anticancer Drug Discovery.- Accessing Anti-Cancer Natural Products by Plant Cell Culture.- Natural Products as Tools for Discovering New Cancer Targets.- Index.
Zusammenfassung
This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools for new target generation , new approaches to cancer drug discovery through natural products based lead generation, and enabling technologies which leverage the unique attributes of natural products.
Zusatztext
From the reviews:
“This book covers a range of topics related to drug discovery, natural product chemistry, cancer biology, and chemical biology. … value to researchers in both academia and the pharmaceutical industry who are involved in the study and development of natural products as potential chemotherapeutic agents. It also will be helpful to basic biomedical scientists and clinicians as a quick overview of this area of research and its recent developments. … also provides a critical assessment of the challenges that researchers in this research field face.” (Bao Ting Zhu, Doody’s Review Service, March, 2013)
Bericht
From the reviews:
"This book covers a range of topics related to drug discovery, natural product chemistry, cancer biology, and chemical biology. ... value to researchers in both academia and the pharmaceutical industry who are involved in the study and development of natural products as potential chemotherapeutic agents. It also will be helpful to basic biomedical scientists and clinicians as a quick overview of this area of research and its recent developments. ... also provides a critical assessment of the challenges that researchers in this research field face." (Bao Ting Zhu, Doody's Review Service, March, 2013)
