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Informationen zum Autor Michael Ellenbecker , Emeritus Professor of Occupational and Environmental Hygiene and Director of the Toxics Use Reduction Institute at the University of Massachusetts Lowell, has published widely on the measurement and control of airborne contaminants. He is co-author of the Wiley textbook Ventilation for Control of the Work Environment , 2d edition. For the past ten years he has led the nanoparticle health and safety efforts at UMass Lowell. Candace Tsai , Assistant Professor of Occupational Health and Industrial Hygiene at Purdue University, and previously Manager for EHS research at UMass Lowell, has led groundbreaking research in exposure assessment and engineering controls associated with nanotechnology development. She received her doctorate in occupational and environmental hygiene and cleaner production at UMass Lowell. Dr. Tsai also has Master's degrees in chemical engineering and management science of business administration. Dr. Tsai has evaluated the potential for nanoparticle exposure in laboratories at many universities and private companies, and developed control techniques and strategies to eliminate exposure in more than a dozen of them. Klappentext Addresses health and safety issues associated with workplace Nanoparticle exposures* Describes methods to evaluate and control worker exposures to engineered nanoparticles* Provides guidance for concerned EHS professionals on acceptable levels of exposure to nanoparticles* Includes documentation on best practices to be followed by all researchers when working with engineered nanoparticles* Describes current knowledge on toxicity of nanoparticles* Includes coverage on Routes of Exposure for Engineered Nanoparticles Zusammenfassung While invaluable for their uses in medicine as a drug delivery system or as an imaging agent in cancer detection, nanoparticles do present possible medical and environmental dangers. Inhaltsverzeichnis Preface xiii 1 Introduction 1 1.1 Why A Book on Nanotechnology Health and Safety? 1 1.2 Some Scenarios 3 1.3 Organization of the Material 5 1.4 Our Approach to Nanoparticle Health and Safety 5 References 7 2 What is a Nanoparticle? 8 2.1 Nanotechnology, Nanomaterials, and Nanoparticles 9 2.1.1 Nanotechnology 9 2.1.2 Nanomaterial 9 2.1.3 Nanoparticle 9 2.2 Naturally Occurring Nanoparticles 10 2.3 Industrial Nanoparticles 12 2.4 Engineered Nanoparticles 14 2.4.1 Carbon Nanotubes 15 2.4.2 Fullerenes 17 2.4.3 Quantum Dots 17 2.5 Emerging Uses for Engineered Nanoparticles 19 2.6 Other Useful Definitions 20 2.6.1 Aerosol 20 2.6.2 Particle Inertia 21 2.6.3 Brownian Motion 22 2.6.4 Particle Diameter 23 2.6.5 Agglomerate versus Aggregate 24 2.7 Summary 25 References 26 3 Why are we Concerned? The Unique Properties of Nanoparticles 28 3.1 Surface?]to?]Volume Ratio 28 3.2 Particle Size 30 3.3 Particle Concentration 32 3.4 Dose Metrics: Particle Number, Surface Area, Morphology, and Surface Properties 33 3.5 Implications for the Occupational and Environmental Health Impacts of Nanoparticles 33 3.5.1 Respiratory Deposition 33 3.5.2 Skin Penetration 34 3.6 Implications for Physical Risks 35 3.6.1 Introduction 35 3.6.2 Current Status 35 3.6.3 Conclusions 36 3.7 Summary 37 References 37 4 Routes of Exposure for Engineered Nanoparticles 39 4.1 Introduction 39 4.2 Engineered Nanoparticle Exposure through Inhalation 40 4.2.1 Human Respiratory System 40 4.2.2 Particle Deposition in the Respiratory System 43 4.3 Engineered Nanoparticle Exposure Through Dermal Contact 46 4.4 Engineered Nanoparticle Exp...
