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Zusatztext A general overview of biological inorganic chemistry as well as a fascinating novel view of the nature of living systems and their evolution ... The authors have created a text that nicely complements the usual chapters found in advanced inorganic and biochemistry text books ... The principles are presented with clear explanations in a relaxed, conversational writing style. The use of clear and detailed drawings, on nearly every page, enhances the text ... a valuable introductory guide to all aspects of the wild and wonderful world of bioinorganic chemistry. Klappentext Twenty inorganic elements, mostly metal ions, are consistently found in living systems and are essential for living systems to function correctly. This text discusses, describes and explains the functional relevance of those elements: the reasons for their selection; the processes of their uptake; transport and final localization in cells; the regulation of these processes; and the interactive network of their reactions that connects the in vivo inorganic elements to the environment and to the genome. The volume has been thoroughly revised for this second edition and includes a discussion of the link to the genome of the uptake and transfer of inorganic elements and the regulation of homeostasis, the functional co-operative activities of the elements, the interaction with the environment, and the evolution of usage. Recent structural and mechanistic knowledge of many biomolecules and organelles is also included. Zusammenfassung This text describes the functional role of the twenty inorganic elements essential to life in living organisms. Inhaltsverzeichnis The chemical and physical factors controlling the elements of life 2: The principles of the uptake and chemical speciation of the elements in biology 3: Physical separations of elements: compartments and zones in biology 4: Kinetic considerations of chemiscal reactions, catalysis, and control 5: Energy in biological systems and hydrogen biochemistry 6: The role of biological macromolecules and polymers 7: The functional value of the chemical elements in biological systems The roles of individual elements in biology 9: The biological chemistry of magnesium: phosphate metabolism 10: Calcium: controls and triggers 11: Zinc: Lewis acid catalysis and regulation 12: Non-haem iron: redox reactions and controls 13: Haen iron: coupled redox reactions 14: Manganese: dioxygen evolution and glycosylation 15: Copper: extracytoplasmic oxidases and matrix formation 16: Nickel and cobalt: remnants of early life 17: Molybdenum, tungsten, vanadium, and chromium 18: Phosphate, silica, and chloride: acid-base non-metals 19: Sulphur, selenium, and the halogens: redox non-metals 20: Integrated living systems of elements ...
