Dna Microarrays and Gene Expression - From Experiments to Data Analysis and Modeling

Klappentext First published in 2002, this is a concise, inter-disciplinary introduction to DNA microarray technology, which is revolutionizing biology and medicine. Zusammenfassung DNA microarrays are in the process of revolutionizing biology and medicine. They can provide a snapshot of the level of gene expression in a cell and are therefore a powerful tool with which to study biological phenomena at the molecular level. This 2002 book explores this powerful technology. Inhaltsverzeichnis Preface; 1. A brief history of genomics; 2. DNA array formats; 3. DNA array readout methods; 4. Gene expression profiling experiments: problems, pitfalls and solutions; 5. Statistical analysis of array data: inferring changes; 6. Statistical analysis of array data: dimensionality reduction, clustering, and regulatory regions; 7. Survey of current DNA array applications; 8. Systems biology: overview of regulatory, metabolic and signaling networks.

Produktdetails

• Autoren: Pierre Baldi, Pierre (University of California Baldi, Pierre Hatfield Baldi, Baldi Pierre, G. Wesley Hatfield, Hatfield G. Wesley
• Verlag: Cambridge University Press ELT
• Sprache: Englisch
• Produktform: Taschenbuch
• Erschienen: 28.04.2011
• EAN: 9780521176354
• ISBN: 978-0-521-17635-4
• Seiten: 230
• Themen: Naturwissenschaften, Medizin, Informatik, Technik > Biologie > Genetik, Gentechnik; Microbiology (non-medical), SCIENCE / Life Sciences / Molecular Biology, SCIENCE / Life Sciences / Genetics & Genomics, SCIENCE / Life Sciences / Microbiology, molecular biology, Genetic Engineering, Genetics (non-medical), Dna & Genome, SCIENCE / Bioinformatics, Computational biology / bioinformatics