5-HT4 Receptors in the Brain and Periphery

This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.

Inhaltsverzeichnis

1. Medicinal Chemistry of 5-HT4 Receptor Ligands.- 2. Molecular Biology of 5-HT4 Receptors.- 3. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles.- 4. Central 5-HT4 Receptors: Electrophysiology.- 5. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors.- 6. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors.- 7. 5-HT4 Receptors in Gastrointestinal Tract.- 8. 5-HT4 Receptors in Lower Urinary Tract Tissues.- 9. The 5-HT4 Receptor in the Adrenal Gland.- 10. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists.

Produktdetails

• Mitarbeit: Richard M. Eglen (Herausgeber), Richar M Eglen (Herausgeber), Richard M Eglen (Herausgeber)
• Verlag: Springer, Berlin
• Sprache: Englisch
• Produktform: Taschenbuch
• Erschienen: 14.11.2013
• EAN: 9783662055557
• ISBN: 978-3-662-05555-7
• Seiten: 229
• Abmessung: 155 mm x 13 mm x 235 mm
• Gewicht: 377 g
• Illustration: XIII, 229 p. 19 illus.
• Serien: Biotechnology Intelligence Unit; Biotechnology Intelligence Unit
• Thema: Naturwissenschaften, Medizin, Informatik, Technik > Biologie > Biochemie, Biophysik