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Informationen zum Autor Ali! Shakir ; Friedman! Scott L. Zusammenfassung This book presents information summarizing the current understanding of a range of liver diseases, and reviews some key diagnostic and therapeutic advances. Inhaltsverzeichnis VOLUME 1: LIVER DISEASES: PATHWAYS! MEDIATORS AND REGULATION : Section I: Liver Diseases: Mediators and Regulation: Ubiquitin - Proteasome Pathway in the Pathogenesis of Liver Disease; Bardag-Gorce; Collagen Gene Regulation in the Hepatic Stellate Cell; Rippe; CYP2F1-Biochemical and Toxicological Aspects and Role in Alcohol-induced Liver Injury; Cederbaum; Alcohol and Methyl Transfer: Implications for Alcohol-Related Hepatocarcinogenesis; Menthionine Adenosyltransferase and S-adenosylmethionine in Liver Health and Disease; Acetone Metabolism in the Liver; Oxidative Stress and Liver Fibrosis: From Liver Injury to Modulation of Cell Signalling and Response; Role of Nitric Oxide in Liver Disorders; Renin-Angiotensin System in Liver Fibrosis Section II: Immunological Basis of Liver Injury: Cell and Molecular Mechanisms in the Development of Chronic Liver Inflammation; Role of Activated Macrophages in Liver Disease; Investigations into Basis for Immune Recognition of Cellular Targets in Primary Biliary Cirrhosis; Cross Talk of Hepatocytes and Nonparenchymal Liver Cells in Physiology and Pathology: Monoxides and Eicosanoids; Activity of Cytokines in Chronic HCV Infection and Influence of Antiviral Drugs; Role of Chemokines in Liver Pathophysiology VOLUME 2: CLINICAL LIVER DISEASES: PATHOPHYSIOLOGY! DIAGNOSTIC AND THERAPEUTIC INSIGHTS: Section III: Clinical Liver Disease Pathophysiology: Nonalcoholic Fatty Liver Diseases: Clinical and Pathophysiological Features; Genetic Basis of Hepatocellular Cancer; Haemochromatosis: Recent Advances; Pathophysiology of Cirrhotic Ascites: Recent Advances; Cryptogenic Hepatitis; HIV-1 and the Liver; Cell Death by Necrosis: Mechanisms and Interception in the Liver; Fulminant Hepatic Failure: Etiology! Pathogenesis! and Treatment Section IV: Therapeutic and Diagnostic Insights: Advances in Biology and Therapy of Hepatitis B Virus Infection; Hepatitis C Virus: Molecular Virology and Therapeutic Targets; Drug Targeting to Hepatic Stellate Cel ...