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Informationen zum Autor Mark Walker and Ralph Rapley are the authors of Route Maps in Gene Technology, published by Wiley. Klappentext Gene-based techniques have revolutionized our understanding of biology and had a direct impact on many aspects of our lives, from clinical medicine to agriculture. Route Maps takes a fresh look at this pivotal and exciting subject, within the larger context of molecular biology as a whole. Rather than follow a traditional 'narrative', Route Maps employs an innovative structure, made up of discrete units that allow the reader to choose from any number of pathways in discovering the concepts of molecular biology, the principles of a recombinant DNA technology and its key methods. Route Maps is written primarily as an introductory text for undergraduate and graduate students in all areas of the life sciences, for medical students, for qualified clinicians and indeed for anyone interested in learning about recombinant DNA technologies and their applications. It is also a valuable revision guide for students who have taken a course in molecular biology. Zusammenfassung Gene-based techniques have revolutionized our understanding of biology and had a direct impact on many aspects of our lives! from clinical medicine to agriculture. This book allows the reader to choose from pathways in discovering the concepts of molecular biology! the principles of a recombinant DNA technology and its key methods. Inhaltsverzeichnis Preface. About the Route Maps format. The Concept Of Genes Is Developed. Genes Are Located To Chromosomes. Genes Are Composed Of DNA. The Chemical Building Blocks Of Nucelic Acids. Formation Of The DNA Double Helix. Packaging Of DNA Within Cells. Chromatin Structure And The Functional Activity Of Genes. Types And Functions Of DNA-Protein Interactions. Organization Of Genomes Into Multiple Chromosomes. Distribution Of Nucleic Acids Within Eukaryotic Cells. Types Of RNA Molecules. The Anatomy Of Eukaryotic Chromosomes. The Organisation Of Genes Within Chromosomes. The Molecular Anatomy Of Eukaryotic Genes. Chromosome Aberrations And Human Disease. Types Of Mutations And Their Effects. Forms Of Chemically Altered DNA; DNA Repair Mechanisms. Linkage Analysis. Pedigree Analysis And Modes Of Inheritance. Genes Dictate The Nature Of Proteins. The Nature Of The Genetic Code. Transcription: Forming Genetic Messages. Post-Transcriptional Processing Of Messenger RNA. Transfer And Ribosomal RNA Processing/Modification. Mechanisms Regulating Gene Expression. Transcriptional Regulatory Sequences. Operons And Prokaryotic Control Of Gene Expression. Transcription Factors And Gene Expression. In Vivo Translation: Decoding Genetic Messages. Sequences Involved In Cellular Protein Targeting. Eukaryotic Cell Division: Mitosis And Meiosis. Molecular Mechanisms Of Cell Cycle Control. Genetic Recombination Mechanisms. Gene Transfer During Bacterial Reproduction. Transposable Genetic Elements: Transposons. In Vivo DNA Replication. Genetic Control Of Development. The Natural Biology Of Bacteriophages. Bacteriophage Genetics. Recombinant DNA Technology. Enzymes Commonly Used In Molecular Biology Methods. Restriction Endonucleases. Restriction Fragment Length Polymorphisms. Isolation Of Nucleic Acids From Cells And Tissues. Visualising Mucleic Acids. Electrophoresis Of Nucleic Acids. In Vitro Hybridisation. Types Of Hybridisation Assay Formats. Southern Blotting; In Situ Hybridisation. Measuring Transcriptional Activity Via Messenger...
