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In the past, insecticide development has been guided mostly by chemo-rational and bio-rational design based on understanding of the physiology and ecology of insects and crops. A limitation in each new class of compounds is the evolution of resistance in populations of key pests, which ultimately leads to control failures. This phenomenon and the desire to produce more selective and biorational compounds serve as the driving force to develop advanced technologies for insecticide design. Among the highlights of this book are the use of nanotechnology to increase potency of available insecticides, the use of genetic engineering techniques for controlling insect pests, the development of novel insecticides that bind to unique biochemical receptors, the exploration of natural products as a source for environmentally acceptable insecticides, and the use of insect genomics and cell lines for determining biological and biochemical modes of action of new insecticides.
Inhaltsverzeichnis
Nanosuspensions: Emerging Novel Agrochemical Formulations.- Pharmacokinetics: Computational Versus Experimental Approaches to Optimize Insecticidal Chemistry.- High-Throughput Screening and Insect Genomics for New Insecticide Leads.- Transgenic and Paratransgenic Insects in Crop Protection.- Future Insecticides Targeting Genes Involved in the Regulation of Molting and Metamorphosis.- Trypsin Modulating Oostatic Factor for Developing Resistant Crops.- Nicotinic Acetylcholine Receptors as a Continuous Source for Rational Insecticides.- Mitochondrial Electron Transport Complexes as Biochemical Target Sites for Insecticides and Acaricids.- Inhibition of Programmed Cell Death by Baculoviruses: Potential in Pest-Management Strategies.- Plant Natural Products as a Source for Developing Environmentally Acceptable Insecticides.- Essential Oils as Biorational Insecticides-Potency and Mode of Action.- Insect Cell Lines as Tools in Insecticide Mode of Action Research.
Zusammenfassung
In the past, insecticide development has been guided mostly by chemo-rational and bio-rational design based on understanding of the physiology and ecology of insects and crops. A limitation in each new class of compounds is the evolution of resistance in populations of key pests, which ultimately leads to control failures. This phenomenon and the desire to produce more selective and biorational compounds serve as the driving force to develop advanced technologies for insecticide design. Among the highlights of this book are the use of nanotechnology to increase potency of available insecticides, the use of genetic engineering techniques for controlling insect pests, the development of novel insecticides that bind to unique biochemical receptors, the exploration of natural products as a source for environmentally acceptable insecticides, and the use of insect genomics and cell lines for determining biological and biochemical modes of action of new insecticides.
