Ulteriori informazioni
Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections - Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics - that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
Bioarrays: From Basics to Diagnostics will serve as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
Sommario
Bioarray Technology Platforms.- Investigation of Tumor Metastasis by Using cDNA Microarrays.- From Tissue Samples to Tumor Markers.- Experimental Design for Gene Expression Analysis.- From Microarrays to Gene Networks.- Biomarkers And Clinical Genomics.- Reduction in Sample Heterogeneity Leads to Increased Microarray Sensitivity.- Genomics to Identify Biomarkers of Normal Brain Aging.- Gene Expression Profiling for Biomarker Discovery.- Array-Based Comparative Genomic Hybridization.- Regional Specialization of Endothelial Cells as Revealed by Genomic Analysis.- Biomarker Identification by Using Clinical Proteomics and Glycomics.- Identification of Target Antigens in CNS Inflammation by Protein Array Technique.- Differential Protein Expression, Protein Profiles of Human Gliomas, and Clinical Implications.- Antibody-Based Microarrays.- Glycoprofiling by DNA Sequencer-Aided Fluorophore-Assisted Carbohydrate Electrophoresis.- High-Throughput Carbohydrate Microarray Technology.- Emerging Technologies in Diagnostics.- Microarrays and Blood Diagnostics.- "Lab-on-a-Chip" Devices for Cellular Arrays Based on Dielectrophoresis.- Genetic Disorders and Approaches to Their Prevention.
Riassunto
Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
Bioarrays: From Basics to Diagnostics will serve as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
Testo aggiuntivo
From the reviews:
"This book compiles various array techniques as applied to profiling of disease states. Included are DNA, protein, and carbohydrate-based methods. … is directed at working scientists interested in the application of array procedures for diagnostic uses. Research fellows and laboratory heads might find material of interest. The editor has selected a broad range of collaborating authors with extensive background in this area. … Each chapter is accompanied by a useful bibliography." (Eugene A Davidson, Doody’s Review Service, October, 2007)
Relazione
From the reviews:
"This book compiles various array techniques as applied to profiling of disease states. Included are DNA, protein, and carbohydrate-based methods. ... is directed at working scientists interested in the application of array procedures for diagnostic uses. Research fellows and laboratory heads might find material of interest. The editor has selected a broad range of collaborating authors with extensive background in this area. ... Each chapter is accompanied by a useful bibliography." (Eugene A Davidson, Doody's Review Service, October, 2007)
