Coalescent Theory - An Introduction

Informationen zum Autor John Wakeley is Professor and Chairman of Biology at Harvard University. He has worked extensively in coalescent theory. His research has focussed on populations structured by geography and limited migration. Using coalescent models! Dr. Wakeley has addressed questions about the current and historical demography of humans and other species. In May 2004! Dr. Wakeley received a 2002 Presidential Early Career Award for Scientists and Engineers. Zusammenfassung This textbook provides the foundation for molecular population genetics and genomics. It shows the conceptual framework for studies of DNA sequence variation within species! and is the source of essential tools for making inferences about mutation! recombination! population structure and natural selection from DNA sequence data. Inhaltsverzeichnis 1. Gene Genealogies.- 2. Probability Theory.- 3. The Coalescent.- 4. Neutral Genetic Variation.- 5. The Structured Coalescent.- 6. Separation of Time Scales.- 7. Ancestral Graphs.- 8. Simulations and Inference.- Bibliography.- Index.

Dettagli sul prodotto

• Autori: John Wakeley, John Wakely
• Editore: Macmillan Learning
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 02.06.2008
• EAN: 9780974707754
• ISBN: 978-0-9747077-5-4
• Pagine: 326
• Dimensioni: 178 mm x 233 mm x 18 mm
• Categorie: Scienze naturali, medicina, informatica, tecnica > Biologia > Genetica, tecnica genetica; B, genetics, Genetics and Genomics, Biomedical and Life Sciences