Angiogenesis in Inflammation: Mechanisms and Clinical Correlates

Angiogenesis is an essential component of inflammation and its resolution. Traditionally, mechanisms of angiogenesis in inflammation were inferred from tumour angiogenesis. However, research in recent years has extracted the similarities and dissimilarities between these processes.

This volume shows how the lessons learned from tumour biology have been applied to inflammation. It develops current knowledge on molecular and cellular mechanisms as they relate to inflammation, including acute and chronic inflammation and neurogenic inflammation, It explains the roles of the multiple cellular components of inflammation, such as fibroblasts, dendritic cells and lymphocytes.

The book shows how this knowledge is being used in the discovery of novel therapeutics. It brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and human disease.

Sommario

Neurogenic angiogenesis and inflammation.- The angiogenic drive in chronic inflammation: Hypoxia and the cytokine milieu.- Dendritic cells and angiogenesis.- The lymphocyte in inflammatory angiogenesis.- The fibroblast and myofibroblast in inflammatory angiogenesis.- Chemokines and cytokines in inflammatory angiogenesis.- Modelling angiogenesis in inflammation.- Angiogenesis in the inflammation of arthritis.

Riassunto

Angiogenesis is an essential component of inflammation and its resolution. Traditionally, mechanisms of angiogenesis in inflammation were inferred from tumour angiogenesis. However, research in recent years has extracted the similarities and dissimilarities between these processes.

This volume shows how the lessons learned from tumour biology have been applied to inflammation. It develops current knowledge on molecular and cellular mechanisms as they relate to inflammation, including acute and chronic inflammation and neurogenic inflammation, It explains the roles of the multiple cellular components of inflammation, such as fibroblasts, dendritic cells and lymphocytes.

The book shows how this knowledge is being used in the discovery of novel therapeutics. It brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and human disease.

Dettagli sul prodotto

• Con la collaborazione di: A Walsh (Editore), A Walsh (Editore), Michae Seed (Editore), Michael Seed (Editore), Michael P. Seed (Editore), Michael P. (Hrsg.) Seed (Editore), David A. Walsh (Editore), David A. (Hrsg.) Walsh (Editore)
• Editore: Springer Basel AG
• Lingue: Inglese
• Formato: Copertina rigida
• Pubblicazione: 01.01.2008
• EAN: 9783764376260
• ISBN: 978-3-7643-7626-0
• Pagine: 180
• Dimensioni: 174 mm x 239 mm x 20 mm
• Peso: 582 g
• Serie: Progress in Inflammation Research; Progress in Inflammation Research
• Categorie: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche non cliniche; Tumor, Onkologie, B, Zellbiologie (Zytologie), Immunology, Klinische und Innere Medizin, Kardiologie, Angiologie, INTERNAL MEDICINE, Oncology, angiology, Biomedical and Life Sciences, Cancer Research, Cellular biology (cytology), Biomedical Research, Clinical & internal medicine, Cell Biology, Cardiovascular medicine, Clinical and internal medicine, Cancer Biology