Fr. 279.00

Analysis of Drug Impurities

Tedesco · Copertina rigida

Spedizione di solito entro 1 a 3 settimane (non disponibile a breve termine)

Descrizione

Ulteriori informazioni

Informationen zum Autor Richard Smith is Director, Analytical Sciences at GlaxoSmithKline Research and Development, Tonbridge, UK and Michael Webb is Director, Analytical Sciences at GlaxoSmithKline Research and Development, Stevenage, UK. Contributors to the book: Dr Linda Ng Dr George Lunn Dr Patrick Faustino Dr Dave Elder Dr Mark R. Hadley Dr Peter Skett Dr Gary E. Martin Dr Ian Jones Dr Janet Hammond Dr Gerald Terfloth Dr Frank Cottee Klappentext A key component of the overall quality of a pharmaceutical is control of impurities, as their presence, even in small amounts, may affect drug safety and efficacy. The identification and quantification of impurities to acceptable standards presents a significant challenge to the analytical chemist. Analytical science is developing rapidly and provides increasing opportunity to identify the structure, and therefore the origin and safety implications of these impurities, and the challenges of their measurement drives the development of modern quantitative methods. Written for both practicing and student analytical chemists, Analysis of Drug Impurities provides a detailed overview of the challenges and the techniques available to permit accurate identification and quantification of drug impurities. Zusammenfassung A key component of the overall quality of a pharmaceutical is control of impurities! as their presence! even in small amounts! may affect drug safety and efficacy. The identification and quantification of impurities to acceptable standards presents a significant challenge to the analytical chemist. Inhaltsverzeichnis 1. Organic impurities in drug substances: origin, control and measurement. . 2. Organic impurities in drug products: origin, control and measurement. 3. Stereochemical impurities. . 4. Low level measurement of potent toxins. . 5. A systematic approach to impurity identification. . 6. The use chromatography and on-line structural elucidation using spectroscopy . 7. Preparative isolation of impurities. . 8. Impact of continuous processing. References. Index ...

Sommario

1. Organic impurities in drug substances: origin, control andmeasurement.
.

2. Organic impurities in drug products: origin, control andmeasurement.

3. Stereochemical impurities.

.

4. Low level measurement of potent toxins.

.

5. A systematic approach to impurity identification.

.

6. The use chromatography and on-line structural elucidationusing spectroscopy .

7. Preparative isolation of impurities.

.

8. Impact of continuous processing.

References.

Index

Relazione

"This book can be recommended to not only analytical chemists but also scientists working in the field of pharmaceutical analysis." ( Analytical and Bioanalytical Chemistry , November 2007)

Dettagli sul prodotto

Autori Smith, Richard Smith, Richard J. Smith, Richard J. (GlaxoSmithKline Smith, Richard J. Webb Smith, Michael Webb
Con la collaborazione di Richard J Smith (Editore), Richard J. Smith (Editore), Richard J. (GlaxoSmithKline Smith (Editore), Michael L Webb (Editore), Michael L. Webb (Editore), Michael L. (GlaxoSmithKline Webb (Editore)
Editore Wiley, John and Sons Ltd
 
Lingue Tedesco
Formato Copertina rigida
Pubblicazione 04.04.2007
 
EAN 9781405133586
ISBN 978-1-4051-3358-6
Pagine 288
Serie Sheffield Analytical Chemistry Series
Analytical Chemistry
Sheffield Analytical Chemistry Series
Sheffield Analytical Chemistry
Categoria Scienze naturali, medicina, informatica, tecnica > Medicina > Farmacia

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