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Informationen zum Autor Lothar Kanz is the editor of Hematopoietic Stem Cells VI, Volume 1106, published by Wiley. Katja C. Weisel is the editor of Hematopoietic Stem Cells VI, Volume 1106, published by Wiley. Klappentext Stem cell research holds great promise for therapeutic applications. This rapidly advancing field is the focus of the biennial international symposium and workshop whose proceedings are contained within this volume. The major topics covered are stem cell function, including self-renewal, survival, migration, and regulation; the stem cell niche; stem cell fate as lineage commitment takes place; malignant hematopoiesis; hematopoiesis regulators; and embryonic stem cells and plasticity. As with previous volumes in this unique series of proceedings, it is hoped that further cooperation and collaborative projects will be generated by disseminating these presentations widely. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung Stem cell research holds great promise for therapeutic applications. This rapidly advancing field is the focus of the biennial international symposium and workshop whose proceedings are contained within this volume. Inhaltsverzeichnis Introduction: Katja C. Weisel, John E. Dick, Willem E. Fibbe, and Lothar Kanz. Part I: Stem Cell Function:. 1. AMD3100 and CD26 Modulate Mobilization, Engraftment, and Survival of Hematopoietic Stem and Progenitor Cells Mediated by the SDF-1/CXCL12-CXCR4 Axis: Hal E. Broxmeyer, Giao Hangoc, Scott Cooper, Timothy Campbell, Shigeki Ito, and Charlie Mantel. 2. The Stem Cell Continuum: Cell Cycle, Injury, and Phenotype Lability: Peter J. Quesenberry, Gerald Colvin, Gerri Dooner, Mark Dooner, Jason M. Aliotta, and Kevin Johnson. 3. Inference, Validation, and Dynamic Modeling of Transcription Networks in Multipotent Hematopoietic Cells: Shamit Soneji, Sui Huang, Matthew Loose, Ian John Donaldson, Roger Patient, Berthold Gottgens, Tariq Enver, and Gillian May. Part II: Stem Cell Niche:. 4. Maintenance of Quiescent Hematopoietic Stem Cells in the Osteoblastic Niche: Fumio Arai and Toshio Suda. 5. Cytokine Signaling, Lipid Raft Clustering, and HSC Hibernation: Satoshi Yamazaki, Atsushi Iwama, Yohei Morita, Koji Eto, Hideo Ema, and Hiromitsu Nakauchi. 6. Dormant and Self-Renewing Hematopoietic Stem Cells and Their Niches: Anne Wilson, Gabriela M. Oser, Maike Jaworski, William E. Blanco-Bose, Elisa Laurenti, Christelle Adolphe, Marieke A. Essers, H. Robson MacDonald, and Andreas Trumpp. Part III: Stem Cell Fate:. 7. Cartography of Hematopoietic Stem Cell Commitment Dependent upon a Reporter for Transcription Factor Activation: Koichi Akashi. 8. Gradients of Antigen Expression and Developmental Potential in Hematopoiesis: Jae-Yong Kwak, Scott Cho, and Gerald J. Spangrude. 9. Biological and Molecular Evidence for Existence of Lymphoid-Primed Multipotent Progenitors: Sidinh Luc, Natalija Buza-Vidas, and Sten Eirik W. Jacobsen. Part IV: Malignant Hematopoiesis:. 10. Insertional Mutagenesis by Replication-Deficient Retroviral Vectors Encoding the Large T Oncogene: Zhixiong Li, Olga S. Kustikova, Kenji Kamino, Thomas Neumann, Mathias Rhein, Elke Grassman, Boris Fehse, and Christopher Baum. 11. NUP98 Dysregulation in Myeloid Leukemogene...
