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Advanced Extraction Techniques: Anti-Doping & Forensic Approaches for Drug Testing delivers a comprehensive and practical guide to the modern extraction strategies essential for detecting drugs and toxic agents in complex biological matrices. Emphasizing the foundational role of sample preparation, this book shows how carefully optimized extraction methods shape the accuracy, sensitivity, and legal defensibility of toxicological results across forensic, clinical, and anti-doping environments.
The book explores a broad range of biological specimens, from routine matrices such as blood, urine, and plasma to alternative samples including hair, oral fluid, nails, vitreous humor, and meconium. It also addresses key analytical challenges such as matrix effects, protein binding, phospholipid interference, and analyte instability. Readers gain clear insight into how extraction influences downstream performance in LC MS/MS and other related techniques.
Key highlights include:
· Comprehensive discussion of liquid-liquid extraction, solid-phase extraction, microextraction techniques etc.
· Practical guidance for enhancing detection of amphetamines, antihistamines, NSAIDs, corticosteroids, anabolic steroids, peptides, bisphosphonates, ITPP, and quaternary ammonium drugs
· Detailed workflows that connect extraction decisions to robust analytical outcomes.
· Focused coverage of anti-doping applications aligned with international testing and accreditation standards.
Ideal for forensic toxicologists, analytical chemists, pharmacologists, anti-doping specialists, and graduate students, this volume bridges scientific principles with applied practice. By demonstrating how optimized
Sommario
Chapter 1 Introduction.- Chapter 2 Forensic Toxicology: Bridging Science, Law, and Public Health.- Chapter 3 Doping In Sport: History, Regulation, and Global Governance.- Chapter 4 The Prohibited Framework: Ensuring Safety and Fair Competition.- Chapter 5 Introduction to Biological Matrices in Forensic Science.- Chapter 6 Extraction Techniques In Forensic Toxicology.- Chapter 7 Comparative Case Studies On Extraction Methods For LC-MS and GC-MS Detection In Forensic Doping Control.
