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This book provides high-quality images along with concise descriptions of the various malformations and neurodevelopmental disorders of the central nervous system (CNS). It serves as a useful guide for pathologists and trainees who do not necessarily have abundant experience in diagnosing CNS malformations and therefore may need an easy-to-understand reference. This atlas shares complex neuropathological findings noted in the vast number of CNS malformations that the authors have encountered over a number of years. Chapters also contain guidelines on how to effectively perform perinatal brain removals at necropsy as well as guidelines for post-mortem examinations of post-mortem brain specimens from patients with malformations.
In addition to illustrations, the book includes easy-to-read descriptions of the different CNS malformations, including gross and microscopic features as well as any known or proposed pathogenesis, and related genetic mutations where applicable. Atlas of Neurodevelopmental Pathology serves as a valuable resource for residents and fellows in neuropathology as well as neuropathologists, and pediatric pathologists who either by interest or necessity wish to have an illustrative reference of CNS malformations.
Sommario
Extraction of Perinatal Brain and Spinal Cord During Necropsy.- Postmortem Examination of Perinatal Brain and Spinal Cord Malformations.- Neural Tube Defects.- Malformations and Disruptions of the Cerebral Hemispheres.- Overgrowth Syndromes.- Prosencephalic Malformations.- Midbrain and Hindbrain Malformations.- Cerebellar Malformations.- Vascular Malformations.- Congenital Cystic Lesions.- Spinal Cord and Spinal Column Formations.- Conjoined Twins.- Genetically Defined Malformations.- Amniotic Band Syndrome (ABS)/Amniotic Rupture Sequence (ARS).
Info autore
Sumit Das
Department of Laboratory Medicine and Pathology
University of Alberta and Stollery Children’s Hospital
Edmonton, Alberta, Canada
Patrick Shannon
Department of Pathology and Laboratory Medicine
Mount Sinai Hospital
Toronto, Ontario, Canada
Yael Fisher
Department of Pathology
Rambam Health Care Campus
Haifa, Israel
Riassunto
This book provides high-quality images along with concise descriptions of the various malformations and neurodevelopmental disorders of the central nervous system (CNS). It serves as a useful guide for pathologists and trainees who do not necessarily have abundant experience in diagnosing CNS malformations and therefore may need an easy-to-understand reference. This atlas shares complex neuropathological findings noted in the vast number of CNS malformations that the authors have encountered over a number of years. Chapters also contain guidelines on how to effectively perform perinatal brain removals at necropsy as well as guidelines for post-mortem examinations of post-mortem brain specimens from patients with malformations.
In addition to illustrations, the book includes easy-to-read descriptions of the different CNS malformations, including gross and microscopic features as well as any known or proposed pathogenesis, and related genetic mutations where applicable. Atlas of Neurodevelopmental Pathology serves as a valuable resource for residents and fellows in neuropathology as well as neuropathologists, and pediatric pathologists who either by interest or necessity wish to have an illustrative reference of CNS malformations.
