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This book provides an overview of neurological disorders that can mimic multiple sclerosis (MS). It offers comprehensive descriptions of a wide range of MS mimickers, highlighting their clinical, biochemical, and imaging similarities and differences compared to MS. This resource is intended to support clinicians particularly neurologists in the differential diagnosis of MS and related demyelinating diseases of the central nervous system, to improve diagnostic accuracy and clinical decision-making.
Sommario
1. Multiple sclerosis (MS).- 2. Autoimmune demyelinating diseases of Central nervous system (CNS).- 3. Autoimmune non-demyelinating diseases of nervous system.- 4. Autoimmune and inflammatory multisystem diseases.- 5. Infectious diseases.- 6. Acquired metabolic and nutritional diseases.- 7. Inherited metabolic diseases.- 8. Neurodegenerative hereditary diseases.- 9. Neoplastic, paraneoplastic, and hematologic disorders.- 10. Primary eye diseases.- 11. Vascular non-inflammatory diseases.- 12. Miscellaneous Diseases and Normal Findings.- 13. Clinical red flags in differential diagnosis of multiple sclerosis.- 14. Demographic and biochemical red flags in differential diagnosis of multiple sclerosis.- 15. Imaging red flags in differential diagnosis of multiple sclerosis.
Info autore
Tomas Uher, MD PhD is neurologist at the Centre for Demyelinating Diseases of the Neurology Department, and at the Center of Clinical Neuroscience at the First Faculty of Medicine, Charles University and General Faculty Hospital in Prague, Czech Republic.
Doctor Tomas Uher earned his medical degree from Charles University in 2006, where he later specialized in neurology. Since 2011, he has also been certified in systemic psychotherapy. In 2012, he completed a Ph.D. in medical psychology at Charles University and joined the Centre for Demyelinating Diseases as a neurologist. In 2013, he obtained board certification in neurology.
He completed a scientific MRI Fellowship at the Buffalo NeuroImaging Analysis Center in USA (9/2013-9/2014), followed by a research fellowship at the University of Melbourne in Australia (9/2018-3/2019). In 2016, he was awarded the MSBase Fellowship.
Together with his colleagues, he has contributed to the field of neuroimaging and fluid biomarker research by applying MRI volumetric analysis and blood and cerebrospinal fluid measures to predict and monitor disease activity in patients with MS. His research also focused on investigating the paraclinical correlates of cognitive impairment in MS. In recent years, he has further explored the determinants and consequences of diagnostic delay in patients with MS.
