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Oxidative stress and neuroinflammation are considered causative factors in various neurological disorders such as Parkinson's and Alzheimer's diseases. Antioxidants are chemicals that bind with oxidative species and nullify their effect from causing damage to biological molecules. Endogenous antioxidants are produced by our body, however most of them are obtained from external sources, primarily through diet, called dietary antioxidants. Major sources of antioxidants are brightly colored fruits, vegetables, cereals, legumes, and herbs. Other very effective sources are berries, green tea, and dark chocolate. These compounds have the potential to hinder neurodegeneration, reduce neuronal death and improve memory as well as cognitive functions. Based on the complex nature of antioxidants and oxidative stress, particular antioxidants such as vitamin E, vitamin C or beta-carotene are beneficial in protecting cells, organs and tissues against oxidative damage.
The Role of Natural Antioxidants in Brain Disorders describes various neuroprotective effects and their physiological phenomenon mediated by antioxidants to maintain and regulate the general health biomarkers against brain disorders. The important role of antioxidants, diet and lifestyle in managing brain disorders is covered, as is their use in conjunction with conventional therapies against oxidative stress. Both exogenous and endogenous antioxidants are explored in full. By focusing on the role of oxidative stress as a triggering mechanism for various brain disorders and the use of antioxidant foods in conjunction with traditional therapies in combating and preventing them, this is a valuable source for researchers in food science, nutrition, health science and physiology.
Sommario
An Introduction: Overview of Nervous system and Brain Disorders.- Pathophysiological Mechanisms of Brain Disorders.- Physiological Significance of Oxidative Stress and Anti-oxidative System.- Oxidative Stress as a triggering Mechanism of Various Diseases.- Chief Role of Neuroinflammation and Oxidative Stress in Brain Disorders.- Available Treatment Modules of Brain disorders.- Antioxidants Mitigate Oxidative Stress: A General Overview.- Role of Endogenous and Dietary Antioxidants in Brain Disorders.- Antioxidants as an Adjuncts to Conventional Therapies against Oxidative Stress.- Role of Antioxidants, and Life Style in Managing Brain Disorders Oxidative Stress Biomarkers and Antioxidant Treatments in Brain Diseases.- Clinical use of antioxidants for the treatment of Brain disorders.
Info autore
Dr. Ali Imran is a Professor in the Department of Food Sciences at Government College University in Faisalabad, Pakistan
Dr. Ghulam Hussain is a Professor in the Department of Physiology at Government College University in Faisalabad,Pakistan
