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Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease: From Basic Science to Clinical Application presents the latest information on the contributions of different FABPs in physiology and pathophysiology, along with their importance in clinical outcomes. The book is divided into six main sections that cover FABP biology and their role in inflammation and diseases, such as cardiovascular, neurological, and liver diseases, to FABPs and their clinical applications.
Each chapter thoroughly reviews current literature, primary research data and clinical cases, providing readers with an overview of the latest information in the expanded field of FABPs. This is an invaluable resource for both researchers and clinicians familiar with and those new to the exciting and everchanging world of fatty acid-binding proteins and clinical disorders.
Sommario
1. Introduction to fatty acid-binding protein family, tissue expression, and ligand specificity
2. Structure and functions of sterol carrier protein-2 and ¿-synuclein
3. FABP gene family: Expression and regulation
4. Involvement of FABPs in cell signaling, gene expression, and angiogenesis
5. Fatty acid-binding proteins in cardiac remodeling
6. Impacts of dietary lipids on cell growth and proliferation: Roles of fatty acid-binding proteins
7. Roles of FABPs on endocannabinoid transport and metabolism
8. Fatty acid-binding proteins inflammatory diseases
9. Fatty acid-binding proteins and immune functions
10. Roles of fatty acid-binding proteins in brain inflammation
11. Fatty acid-binding proteins in adipose tissue inflammation
12. Roles of fatty acid-binding proteins in the development of insulin resistance and type 2 diabetes mellitus
13. Fatty acid-binding proteins in the development and progression of cardiovascular diseases
14. Fatty acid-binding proteins and metabolic syndrome
15. Role of fatty acid-binding proteins in obesity and obesity-mediated diseases
16. Fatty acid-binding proteins and their dysregulation in human diseases
17. Fatty acid-binding proteins and brain diseases
18. Fatty acid-binding proteins and liver diseases
19. Fatty acid-binding proteins: Impacts of injury on cardiac, renal, and intestine tissues
20. Fatty acid-binding proteins in celiac diseases
21. Dysregulation of fatty acid-binding proteins in cancers
22. Fatty acid-binding proteins in prostate cancer
23. Fatty acid-binding proteins in psoriasis
24. Fatty acid-binding proteins and breast cancer
25. Plasma fatty acid-binding proteins as biomarkers of diseases
26. Clinical usefulness of urinary fatty acid-binding proteins in assessing several diseases
27. Fatty acid-binding proteins as therapeutic targets in different diseases
Info autore
Dr. Asim K. Duttaroy is a professor at the Faculty of Medicine, University of Oslo, Oslo, Norway. His research programs focus on the roles of food components on growth and development, as well as in the prevention of diseases such as diabetes and cardiovascular disease. He is also investigating the roles of the antiplatelet and antihypertensive properties of fruits and vegetables. His discoveries of antithrombotic factors in tomatoes and kiwifruits are patented internationally, and three companies (Provexis Limited in the United Kingdom, IDIA AS in Norway, and Genimen Pharmacon in India) are working to commercialize these discoveries. He has published over 265 original contributions and reviews, 6 books, and several book chapters and editorials, and he is the Editor-in-Chief of the journal Food & Nutrition Research, as well as a guest editor of several journals such as Nutrients and Frontiers in Physiology.
