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A reflection of the explosion of research and development in this field, this book explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. It collates recent developments in the field into a state-of-the-art framework for this discipline. A select panel of experts discusses their cutting-edge omics research and novel technologies, supplying a basic platform of methods and applications as well as a multi-omics approach to future endeavors in the fertile areas of omics research.
Sommario
SECTION I: Methodology and ApplicationBioinformatics: A Brief Introduction to Changing Trends in Modern Biology
Nutrigenomics
Omics Approaches in Toxicology Research and Biomedical Applications
Stem Cells: Basics and Therapeutic Applications
Emerging Trends of Nanotechnology in Omics-Based Drug Discovery and Development
Magnetic Nanoparticles in Biomedical Applications
High-Throughput Screening in Medical Diagnosis and Prognosis
High-Throughput Omics: The Application of Automated High-Throughput Methods and Systems for Solutions in Systems Biology
Safety in Diagnostic Imaging Techniques Used in Omics
SECTION II: Empirical ResearchMolecular Genetics of Human Cancers: Modulation of the Tumor Suppressor Function of RB1 Gene Product in Human Vestibular Schwannomas
Forward Genetics Approach in Genomics: Functional Identification of Unknown Genes
Proteomics of Phagosomal Pathogens: Lessons from Listeria monocytogens and New Tools in Immunology
SECTION III: Computational and Systems BiologyIn a Quest to Uncover Governing Principles of Cellular Networks: A Systems Biology Perspective
Intermolecular Interaction in Biological Systems
Implanted Brain-Machine Interfaces in Rats: A Modern Application of Neuromics
SECTION IV: TherapeuticsPharmacogenomics in Development of Disease-Specific Therapeutic Strategy
Omics Approaches in Cancer Biomarker and Targeted Anticancer Drug Discovery
Recent Advances in MicroRNA Expression Profiling Toward a Molecular Anatomy of Tumorigenesis and Applications for Diagnosis, Prognosis, and Therapeutics
Marine Metabolomics in Cancer Chemotherapy
Genome-Wide Association Studies of Type 2 Diabetes: Current Status, Open Challenges, and Future Perspectives
Cardiac Channelopathies: Applications of Genomics and Proteomics in Diagnosis and Therapy
Toward an Omic Perspective on Infectious Disease and Its Therapy: Integrating Immunoinformatics, Immunomics, and Vaccinomics
NeuroAIDS and Omics of HIV Vpr
Neurogenetics and Nutrigenomics of Reward Deficiency Syndrome
SECTION V: Future PerspectiveFuture Perspective: Paving a Path to Optimization of Health
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Debmalya Barh, Kenneth Blum, Margaret A. Madigan
