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Handbook of Sleep Research, Volume 30, provides a comprehensive review of the current status of the neuroscience of sleep research. It begins with an overview of the neural, hormonal and genetic mechanisms of sleep and wake regulation before outlining the various proposed functions of sleep and the role it plays in plasticity, and in learning and memory. Finally, the book discusses disorders of sleep and waking, covering both lifestyle factors that cause disrupted sleep and psychiatric and neurological conditions that contribute to disorders.
Sommario
Theme A: Brain activity during sleep and waking
1. Neuronal activity during the sleep-wake cycle
2. Timing and topography of sleep onset: asynchronies and regional changes of brain activity
3. Local patterns of sleep and wakefulness
4. Hippocampal information processing and homeostatic regulation during REM and non-REM sleep
Theme B: Regulation of Waking and Sleeping
5. The circuit, cellular and synaptic bases of sleep-wake regulation
6. Hypocretin and the regulation of sleep-wake transitions
7. Serotonergic systems in sleep and waking
8. Adenosinergic control of sleep/wake behavior
9. NREM sleep regulation from neuronal assembly to ion
10. Neurobiological mechanism of non-REM sleep
11. The genetic regulation of human sleep-wake rhythms and patterns
12. Circadian and homeostatic regulation of sleep
13. The role of glia in sleep-wake regulation and function
14. Interactions between sleep and breathing
15. Neurobiological parallels, overlaps and divergences of sleep & anaesthesia
Theme C: REM Sleep and Dreaming
16. Neuroanatomical and neurochemical systems involved in REM sleep generation
17. Functions and circuits of REM sleep
18. Structural and functional differences in brain mechanisms of dream recall
19. Consciousness and meta-consciousness during sleep
Theme D: Evolution, Cross-Cultural and Comparative Approaches, and Novel Model Systems
20. Evolution of sleep and adaptive sleeplessness
21. Hunter-gatherer sleep and novel human sleep adaptations
22. Sleep in
Drosophila
23. Sleep, immunity, and stress: novel insights from
Drosophila
24. Sleep in fish models
25. Sleep in aquatic mammals
26. The role of sleep in song learning processes in songbird
Theme E: Sleep, Plasticity, and Memory
27. Sleep and brain development
28. Sleep and plasticity
29. Sleep-wake and cortical synaptic plasticity
30. Sleep stages and neural oscillations: A window into sleep's role in memory consolidation and cognitive abilities
31. Cued memory reactivation: A tool to manipulate memory consolidation during sleep
32. Sleep and memory consolidation: conceptual and methodological challenges
Theme F: Sleep, Emotion, and Motivation
33. The role of sleep in processing emotional information
34. Sleep and emotions: on sleep, emotional memories and depression
35. Motivational processes in the regulation of sleep/wake states
Theme G: Disturbed Sleep
36. The effects of sleep loss on brain functioning
37. Physiological and neurobehavioural consequences of chronic sleep restriction in rodent models
38. Imaging of the sleep disordered brain
39. Sleep impact on perception, memory, and emotion in adults and the effects of early life experience
40. Sleep and driving
41. Drug discovery and emerging treatments for sleep disorders
42. Insomnia pharmacotherapies: pharmacodynamics, strategies, new directions, and key measures in clinical trial investigations
Theme H: Sleep in Aging and Disease
43. Sleep and aging: circadian influences
44. Sleep, physical activity, and cognitive health in older adults
45. Sleep in normal aging, Alzheimer's disease and mild cognitive impairment
46. Sleep in major depression
47. Closing the loop between circadian rhythms, sleep and attention deficit hyperactivity disorder
48. Dissecting brain circuitry for sleep disorder narcolepsy in murine models
49. Rapid Eye Movement Sleep Behavior Disorder: Pathological neural circuits and association with Parkinson's Disease
Info autore
Dr. Dringenberg is professor in the Department of Psychology and the Centre for Neuroscience Studies at Queen’s University, Kingston, Ontario, Canada. He took up his position at Queen’s after completing a Ph.D. in Neuroscience at the University of Western Ontario, Canada, and a post-doctoral fellowship at the Institute of Physiological Psychology, University of Duesseldorf, Germany. Over the last 20 years, research in Dr. Dringenberg’s Neuroplasticity Laboratory has examined the role of various sleep-wake-related neuromodulators in controlling the electrical activity and synaptic plasticity of the neocortex and hippocampus in animal models. Recently, his lab has expanded its focus to also investigate the role of sleep and waking states in memory consolidation in humans. Dr. Dringenberg’s work has been funded by the Natural Sciences and Engineering Research Council of Canada (NSERC); he is the author of more than 80 peer-reviewed publications.
