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One of the primary purposes and obligations of science, in addition to - derstandingnatureingeneralandlifeinparticular, istoassistinenhancing the quality and longevity of life, indeed a most daunting challenge. To be able to meaningfully meet the last of the above expectations, it is nec- sary to provide the practitioner of medicine with diagnostic and predictive capabilities that science will accord when its seemingly disparate parts are melded together and brought to bear on the problems that they face. The development of interdisciplinary activities involving the various basic sciences-biology, physics, chemistry, and mathematics, and their applied counterparts, engineering and technology-is a necessary key to unlocking the mysteries of medicine, which at the moment is a curious admixture of art, craft, and science. Signi?cant strides have been taken during the past decades for putting intoplaceamethodologythattakesintoaccounttheinterplayofthevarious basic sciences. Considerable progress has been made in understanding the role that mechanics has to play in the development of medical procedures. Thiscollectionofsurveyarticlesaddressestheroleofmechanicswithregard to advances in the medical sciences. In particular, these survey articles bring to one's attention the central role played by mathematical modeling in general and the modeling of mechanical issues in particular that have a bearing on the biology, chemistry, and physics of living matter.
Sommario
Rheology of Living Materials.- Biochemical and Biomechanical Aspects of Blood Flow.- Theoretical Modeling of Enlarging Intracranial Aneurysms.- Theoretical Modeling of Cyclically Loaded, Biodegradable Cylinders.- Regulation of Hemostatic System Function by Biochemical and Mechanical Factors.- Mechanical Properties of Human Mineralized Connective Tissues.- Mechanics in Tumor Growth.- Inhomogeneities in Biological Membranes.
Riassunto
This interdisciplinary collection of surveys highlights the central role played by the mathematical modeling of mechanical properties having an effect on the living matter. The book presents in a single, self-contained resource topics that are widely scattered across the literature in a variety of journals having mutually nonintersecting communities of readers, such as applied mathematicians, engineers, biologists, and physicians.
Topics covered include mechanical properties of biological materials, biochemical and biomechanical aspects of blood flow, formation and growth of intracranial aneurysms, modeling of natural tissue substitutes, including cardiovascular and biodegradable stents, regulation of hemostatic system function, and mechanical properties of tumors, bones and cell membranes.
Modeling of Biological Materials may be used in interdisciplinary, introductory courses covering various biomechanical topics for graduate students in applied mathematics, engineering, and biomedicine. The surveys featured in the book will also be a lasting and valuable reference for a wide community of researchers, practitioners, and advanced students in the above-mentioned fields.
