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Informationen zum Autor The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research. Klappentext This book focuses on the factors that maintain stem cells in a pluripontent state or drive them to create differentiated and lineage-committed cells in vitro and in vivo.* Gives a comprehensive overview of current issues in stem cell research* Unites a general consideration of stem cell research with a specific concentration on the key issue of nuclear reprogramming* Discusses important ethical and policy issues which create the framework within which scientists carry out stem cell research* Contributions from leading figures in the field Zusammenfassung This book focuses on the factors that maintain stem cells in a pluripontent state or drive them to create differentiated and lineage-committed cells in vitro and in vivo.* Gives a comprehensive overview of current issues in stem cell research* Unites a general consideration of stem cell research with a specific concentration on the key issue of nuclear reprogramming* Discusses important ethical and policy issues which create the framework within which scientists carry out stem cell research* Contributions from leading figures in the field Inhaltsverzeichnis Chair's Introduction (John Gearhart). What is a stem cell ? Discussion (Davor Solter). Bone-marrow derived hepatocytes - Discussion (Markus Grompe). Normal and neoplastic stem cells - Discussion (Irvin L. Weissman). Multipotent adult progenitor cells: an update - Discussion (Catherine A. Verfaillie). Neural progenitor cells of the adult brain - Discussion (Steven A. Goldman and Fraser Sim). Stem cells in the brain - General Discussion I. Embryonic stem cells: a perspective - Discussion (Martin Evans). Nuclear cloning, epigenetic reprogramming and cellular differentiation - Discussion (Rudolf Jaenisch, Konrad Hochedlinger and Kevin Eggan). General Discussion II. Nuclear reprogramming by xenopus oocytes - Discussion (J.B. Gordon, J.A. Byrne and S. Simonsson). Cardiac stem cells and myocardial regeneration - Discussion (Bernardo Nadal-Ginard, Perio Anversa, Jan Kajstura and Annarosa Leri). Genenration of insulin-producing cells from stem cells - Discussion (Bernat Soria, Enrique Roche, Juan A. Reig and Franz Martin). Cell therapy for Parkinson's disease: problems and prospects - Discussion (Anders Bjorklund). Ethical (and political) issues in research with human stem cells - Discussion (Thomas H. Murray). The regulatory environment - final discussion. Index of contributors. Subject index. ...
Sommario
Chair's Introduction (John Gearhart).
What is a stem cell ? Discussion (Davor Solter).
Bone-marrow derived hepatocytes - Discussion (Markus Grompe).
Normal and neoplastic stem cells - Discussion (Irvin L. Weissman).
Multipotent adult progenitor cells: an update - Discussion (Catherine A. Verfaillie).
Neural progenitor cells of the adult brain - Discussion (Steven A. Goldman and Fraser Sim).
Stem cells in the brain - General Discussion I.
Embryonic stem cells: a perspective - Discussion (Martin Evans).
Nuclear cloning, epigenetic reprogramming and cellular differentiation - Discussion (Rudolf Jaenisch, Konrad Hochedlinger and Kevin Eggan).
General Discussion II.
Nuclear reprogramming by xenopus oocytes - Discussion (J.B. Gordon, J.A. Byrne and S. Simonsson).
Cardiac stem cells and myocardial regeneration - Discussion (Bernardo Nadal-Ginard, Perio Anversa, Jan Kajstura and Annarosa Leri).
Genenration of insulin-producing cells from stem cells - Discussion (Bernat Soria, Enrique Roche, Juan A. Reig and Franz Martin).
Cell therapy for Parkinson's disease: problems and prospects - Discussion (Anders Bjorklund).
Ethical (and political) issues in research with human stem cells - Discussion (Thomas H. Murray).
The regulatory environment - final discussion.
Index of contributors.
Subject index.
Relazione
"...this book provides: a comprehensive overview of current issues in stem cell research, with contributions from leading figures..." ( British Society of Cell Biology , January 2006) "This compact book is easy to read [discussions] provide insights into the practice of science as a deeply human enterprise. I learned a great deal." ( Doody s Health Services ) ...is an essential purchase for all those engaged in stem cell research, whether in the laboratory or the clinic. ( Anticancer Research , 2007)
