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Klappentext Der Begriff familiär-bedingte Krebserkrankung steht für bösartige Erkrankungen, die zurückgehen auf bestimmte Mutationen, die vererbt werden können. Die Forschung auf diesem Gebiet ist im Zuge der Kartierung des menschlichen Genoms rasant fortgeschritten. Damit wird es möglich, Familien mit einem erhöhten Risiko für krebsfördernde Mutationen gezielt zu untersuchen. Zu diesen vererbbaren Krebserkrankungen gehört z.B. der Brustkrebs gebunden an Mutationen im BRCA Gen und der Dickdarmkrebs gebunden an Mutationen im HNPCC. Inhaltsverzeichnis Partial table of contents:OVERVIEWS.The UICC Familial Cancer and Prevention Project (W. Weber).Molecular Epidemiology of Human Cancer (S. Hussain & C. Harris).GENERAL STRATEGIES AND EXPERIENCE.From Nurse to Nodal Points: The Rationale of a Questionnaire and Database to Collect, Validate, and Exchange Information on Familial Cancer (D. Brunetti & W. Weber).Collecting Information About Familial Cancer (W. Weber, et al.).Family History-Based Screening for Colorectal Cancer (D. St. John).Hereditary Tumor Registry in Korea (J.-G. Park).Ethical Issues in Precancer Screening: The Parallel With Huntington Disease (D. Dickenson).Bioethical Concerns With Rights of Patients Receiving Genetic Tests (K. Hoshino).Use of Genetic Information by Private Insurers (R. Pokorski).SPECIFIC FAMILIAL CANCERS.Surgical Management of Familial Adenomatous Polyposis (J. Utsunomiya & N. Gondo).Extracolonic Symptoms of Familial Adenomatous Polyposis and Their Association With a Slow Acetylation Phenotype (R. Scott, et al.).Defining the Clinical Phenotype of Hereditary Nonpolyposis Colorectal Cancer (N. Beck, et al.).Evolution of Neoplasia in Hereditary Nonpolyposis Colorectal Cancer (J. Jass).Surveillance and Management of Hereditary Nonployposis Colorectal Cancer (H. Vasen, et al.).Genetic Diagnosis and Management of Suspected Hereditary Nonpolyposis Colorectal Cancer (J.-G. Park, et al.).The Impact of Living With Hereditary Colorectal Disease (T. Berk).Familial Colorectal Cancer in India: The Tata Memorial Hospital Experience (K. Mohandas).Nationwide Survey and Analysis of the RET Proto-Oncogene in Inherited Medullary Thyroid Carcinoma in Japan (H. Takami).Management of Hereditary Medullary Thyroid Carcinoma (J. Moley & S. Wells).Mapping of Non-BRCA1/2 Breast Cancer Genes (Y. Shugart, et al.).Cancer Risk-Modifying Factors in BRCA1 or BRCA2 Mutation Carriers (T. Rebbeck).Hereditary Multiple Exostoses and Cancer Risk (D. Porter & A. Simpson).WORKSHOP REPORTS.UICC Molecular Biology Workshop Report (R. Scott).Workshop Report 1 (C. Harris).POSTER SESSIONS....
