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Although much progress has been made in the treatment of acute leukemia, there is still vigorous debate over the optimal methods for securing additional gains in event-free survival and for reducing the toxic side effects of "curative" therapy. In Treatment of Acute Leukemias: New Directions for Clinical Research, international experts not only review the state-of-the-art in managing children and adults with acute leukemia, but also debate the pros and cons of current controversial and problematic issues. The book summarizes the best diagnostic and treatment practices for newly diagnosed and relapsed acute lymphoblastic and myeloid leukemia in children, adolescents, and adults. Among the therapies considered are methotrexate, asparaginase, antipurines, epipodophyllotoxins, hematopoietic stem cell transplantation, hematopoietic growth factors, and immunotherapy. Problems of central-nervous-system therapy, minimal residual disease, drug resistance, and directions of future research are also considered. Discussion of each major topic by two distinguished groups of investigators ensures broad and balanced coverage.
Comprehensive and up-to-date, Treatment of Acute Leukemias: New Directions for Clinical Research offers oncologists practical guidelines for precise diagnosis and optimal treatment of childhood and adult acute leukemia, as well as insights into those aspects of patient management most in need of further study and refinement.
Riassunto
Pui (U. of Tennessee Health Science Center) presents 42 papers that are devoted to identifying and discussing pivotal issues that might be resolved through better applications of current methods of leukemia management, rather than waiting for laboratory discoveries to drive change. Chapters look at
Testo aggiuntivo
"...This book offers the best approach to the presentation of problems related to the treatment of the acute leukemias that I know of. The idea of having different groups of investigators give their views on the topics and the emphasis on future directions make it an important contribution to the study of leukemia. Treatment of Acute Leukemias should be read by both adult and pediatric hematologists and oncologists, and it should be required reading for trainees in these disciplines. Dr. Pui, who has already made major contributions through his own work, has added greatly to the future of the field by organizing and editing this impressive book." -New England Journal of Medicine
"...comprehensive and up to date. This is one of the best books produced in recent years on the diagnosis and management of the acute leukaemias." - European Journal of Haematology
Relazione
"...This book offers the best approach to the presentation of problems related to the treatment of the acute leukemias that I know of. The idea of having different groups of investigators give their views on the topics and the emphasis on future directions make it an important contribution to the study of leukemia. Treatment of Acute Leukemias should be read by both adult and pediatric hematologists and oncologists, and it should be required reading for trainees in these disciplines. Dr. Pui, who has already made major contributions through his own work, has added greatly to the future of the field by organizing and editing this impressive book." -New England Journal of Medicine
"...comprehensive and up to date. This is one of the best books produced in recent years on the diagnosis and management of the acute leukaemias." - European Journal of Haematology
